Comparative study of articaine and lidocaine for third molar surgery

Background: This study aims to compare the anesthetic efficacy, postoperative pain, hemorrhage & dry sock incidence of articaine 4% versus lidocaine 2% in inferior alveolar nerve block during impacted lower third molar surgery. Materials and Methods: A prospective randomized study was conducted...

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Main Authors: Shirin Shahnaseri, Navid Mohammadi, Alireza Tamizifar, Seyed Amir Mousavi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2019-08-01
Series:Journal of Craniomaxillofacial Research
Subjects:
Online Access:https://jcr.tums.ac.ir/index.php/jcr/article/view/286
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author Shirin Shahnaseri
Navid Mohammadi
Alireza Tamizifar
Seyed Amir Mousavi
author_facet Shirin Shahnaseri
Navid Mohammadi
Alireza Tamizifar
Seyed Amir Mousavi
author_sort Shirin Shahnaseri
collection DOAJ
description Background: This study aims to compare the anesthetic efficacy, postoperative pain, hemorrhage & dry sock incidence of articaine 4% versus lidocaine 2% in inferior alveolar nerve block during impacted lower third molar surgery. Materials and Methods: A prospective randomized study was conducted on 20 subjects planned for elective surgical removal of bilateral impacted mandibular with similar difficulty indices. A single operator performed all surgeries on basis using 4% articaine or 2% lidocaine as an anesthetic agent and with the same concentration of vasoconstrictor (epinephrine 1:100,1000). Latency, duration of anesthetic effect, intra and post surgical pain experiences, hemorrhage & dry socket occurrences were evaluated with respect to the type of anesthetia. A visual analog scale was used to score pain. Data were analyzed by descriptive statistics, repeated measures ANOVA, Wilcoxon and McNemar’s test (α=0.05). Results: Latency, Intra & Postoperative pain and hemorrhage showed clinical differences in favor of articaine, though statistical significance was not reached. In turn, the mean duration of anesthetic for articain was much extended and showed statistically significant difference. Dry socket incidence consisted of two occurrences (5%) and those two only occurred in Lidocain group. Conclusion: Although 4% articaine offers better pharmacological performance than 2% lidocaine, both articaine and lidocaine have demonstrated adequate, negligible differences and acceptable clinical profiles. For this reason, their use in oral surgery should remain of the professional preference who will evaluate their use base on the necessary surgical time.
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spelling doaj.art-a03511e64aaa429eaa8d967574a3bb662022-12-22T04:07:13ZengTehran University of Medical SciencesJournal of Craniomaxillofacial Research2345-54892345-62132019-08-016110.18502/jcr.v6i1.1627Comparative study of articaine and lidocaine for third molar surgeryShirin Shahnaseri0Navid Mohammadi1Alireza Tamizifar2Seyed Amir Mousavi3Department of Oral and Maxillofacial Surgery, Implant Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.Isfahan University of Medical Sciences, Isfahan, Iran.Department of Oral & Maxillofacial Surgery, Isfahan University of Medical Sciences, Isfahan, Iran.Department of Endodontics, Faculty of Dental Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.Background: This study aims to compare the anesthetic efficacy, postoperative pain, hemorrhage & dry sock incidence of articaine 4% versus lidocaine 2% in inferior alveolar nerve block during impacted lower third molar surgery. Materials and Methods: A prospective randomized study was conducted on 20 subjects planned for elective surgical removal of bilateral impacted mandibular with similar difficulty indices. A single operator performed all surgeries on basis using 4% articaine or 2% lidocaine as an anesthetic agent and with the same concentration of vasoconstrictor (epinephrine 1:100,1000). Latency, duration of anesthetic effect, intra and post surgical pain experiences, hemorrhage & dry socket occurrences were evaluated with respect to the type of anesthetia. A visual analog scale was used to score pain. Data were analyzed by descriptive statistics, repeated measures ANOVA, Wilcoxon and McNemar’s test (α=0.05). Results: Latency, Intra & Postoperative pain and hemorrhage showed clinical differences in favor of articaine, though statistical significance was not reached. In turn, the mean duration of anesthetic for articain was much extended and showed statistically significant difference. Dry socket incidence consisted of two occurrences (5%) and those two only occurred in Lidocain group. Conclusion: Although 4% articaine offers better pharmacological performance than 2% lidocaine, both articaine and lidocaine have demonstrated adequate, negligible differences and acceptable clinical profiles. For this reason, their use in oral surgery should remain of the professional preference who will evaluate their use base on the necessary surgical time.https://jcr.tums.ac.ir/index.php/jcr/article/view/286ArticaineBleedingDry socketIAN bockImpacted lower third molarLidocaine
spellingShingle Shirin Shahnaseri
Navid Mohammadi
Alireza Tamizifar
Seyed Amir Mousavi
Comparative study of articaine and lidocaine for third molar surgery
Journal of Craniomaxillofacial Research
Articaine
Bleeding
Dry socket
IAN bock
Impacted lower third molar
Lidocaine
title Comparative study of articaine and lidocaine for third molar surgery
title_full Comparative study of articaine and lidocaine for third molar surgery
title_fullStr Comparative study of articaine and lidocaine for third molar surgery
title_full_unstemmed Comparative study of articaine and lidocaine for third molar surgery
title_short Comparative study of articaine and lidocaine for third molar surgery
title_sort comparative study of articaine and lidocaine for third molar surgery
topic Articaine
Bleeding
Dry socket
IAN bock
Impacted lower third molar
Lidocaine
url https://jcr.tums.ac.ir/index.php/jcr/article/view/286
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AT navidmohammadi comparativestudyofarticaineandlidocaineforthirdmolarsurgery
AT alirezatamizifar comparativestudyofarticaineandlidocaineforthirdmolarsurgery
AT seyedamirmousavi comparativestudyofarticaineandlidocaineforthirdmolarsurgery