The Impact of Co-occurring Post-traumatic Stress Disorder and Substance Use Disorders on Craving: A Systematic Review of the Literature
The frequent co-occurrence of post-traumatic stress disorder (PTSD) and substance use disorders (SUDs) leads to manifestations of both conditions that are more severe and more resistance to treatment than single disorders. One hypothesis to explain this synergy is the impact of intrusive memories on...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-12-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2021.786664/full |
| _version_ | 1819240951644684288 |
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| author | Fabien Renaud Louise Jakubiec Louise Jakubiec Joel Swendsen Joel Swendsen Melina Fatseas Melina Fatseas |
| author_facet | Fabien Renaud Louise Jakubiec Louise Jakubiec Joel Swendsen Joel Swendsen Melina Fatseas Melina Fatseas |
| author_sort | Fabien Renaud |
| collection | DOAJ |
| description | The frequent co-occurrence of post-traumatic stress disorder (PTSD) and substance use disorders (SUDs) leads to manifestations of both conditions that are more severe and more resistance to treatment than single disorders. One hypothesis to explain this synergy is the impact of intrusive memories on craving which, in turn, increases the risk of relapse among patients with substance use disorders. The aim of this systematic review is to examine this possibility by assessing the impact of PTSD and its symptoms on craving among dual disorder patients. Using PRISMA criteria, four databases were comprehensively searched up to June, 2021, in order to identify all candidate studies based on broad key words. Resulting studies were then selected if they examined the impact of PTSD or PTSD symptoms on craving, and if they used standardized assessments of PTSD, SUD, and craving. Twenty-seven articles matched the selection criteria and were included in this review. PTSD was found to be significantly associated with increased craving levels among patients with alcohol, cannabis, cocaine, tobacco, and other substance use disorders. Exposition to traumatic cues among dual disorder patients was also shown to trigger craving, with an additive effect on craving intensity when exposure to substance-related cues occurred. In addition, certain studies observed a correlation between PTSD symptom severity and craving intensity. Concerning mechanisms underlying these associations, some findings suggest that negative emotional states or emotion dysregulation may play a role in eliciting craving after traumatic exposure. Moreover, these studies suggest that PTSD symptoms may, independently of emotions, act as powerful cues that trigger craving. These findings argue for the need of dual disorder treatment programs that integrate PTSD-focused approaches and emotion regulation strategies, in addition to more traditional interventions for craving management. |
| first_indexed | 2024-12-23T14:16:10Z |
| format | Article |
| id | doaj.art-a037c8e925644c3bbe6fca0617132900 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-12-23T14:16:10Z |
| publishDate | 2021-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-a037c8e925644c3bbe6fca06171329002022-12-21T17:43:54ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402021-12-011210.3389/fpsyt.2021.786664786664The Impact of Co-occurring Post-traumatic Stress Disorder and Substance Use Disorders on Craving: A Systematic Review of the LiteratureFabien Renaud0Louise Jakubiec1Louise Jakubiec2Joel Swendsen3Joel Swendsen4Melina Fatseas5Melina Fatseas6Pôle Inter-établissement d'addictologie, CHU de Bordeaux et Centre Hospitalier Charles Perrens, Bordeaux, FrancePôle Inter-établissement d'addictologie, CHU de Bordeaux et Centre Hospitalier Charles Perrens, Bordeaux, FranceUniversity of Bordeaux/CNRS-UMR 5287, Bordeaux, FranceUniversity of Bordeaux/CNRS-UMR 5287, Bordeaux, FranceEPHE, PSL Research University, Paris, FrancePôle Inter-établissement d'addictologie, CHU de Bordeaux et Centre Hospitalier Charles Perrens, Bordeaux, FranceUniversity of Bordeaux/CNRS-UMR 5287, Bordeaux, FranceThe frequent co-occurrence of post-traumatic stress disorder (PTSD) and substance use disorders (SUDs) leads to manifestations of both conditions that are more severe and more resistance to treatment than single disorders. One hypothesis to explain this synergy is the impact of intrusive memories on craving which, in turn, increases the risk of relapse among patients with substance use disorders. The aim of this systematic review is to examine this possibility by assessing the impact of PTSD and its symptoms on craving among dual disorder patients. Using PRISMA criteria, four databases were comprehensively searched up to June, 2021, in order to identify all candidate studies based on broad key words. Resulting studies were then selected if they examined the impact of PTSD or PTSD symptoms on craving, and if they used standardized assessments of PTSD, SUD, and craving. Twenty-seven articles matched the selection criteria and were included in this review. PTSD was found to be significantly associated with increased craving levels among patients with alcohol, cannabis, cocaine, tobacco, and other substance use disorders. Exposition to traumatic cues among dual disorder patients was also shown to trigger craving, with an additive effect on craving intensity when exposure to substance-related cues occurred. In addition, certain studies observed a correlation between PTSD symptom severity and craving intensity. Concerning mechanisms underlying these associations, some findings suggest that negative emotional states or emotion dysregulation may play a role in eliciting craving after traumatic exposure. Moreover, these studies suggest that PTSD symptoms may, independently of emotions, act as powerful cues that trigger craving. These findings argue for the need of dual disorder treatment programs that integrate PTSD-focused approaches and emotion regulation strategies, in addition to more traditional interventions for craving management.https://www.frontiersin.org/articles/10.3389/fpsyt.2021.786664/fullpost-traumatic stress disorder (PSTD)substance use disorderdual disorder (DD)cravingintegrated treatmentsystematic (literature) review |
| spellingShingle | Fabien Renaud Louise Jakubiec Louise Jakubiec Joel Swendsen Joel Swendsen Melina Fatseas Melina Fatseas The Impact of Co-occurring Post-traumatic Stress Disorder and Substance Use Disorders on Craving: A Systematic Review of the Literature Frontiers in Psychiatry post-traumatic stress disorder (PSTD) substance use disorder dual disorder (DD) craving integrated treatment systematic (literature) review |
| title | The Impact of Co-occurring Post-traumatic Stress Disorder and Substance Use Disorders on Craving: A Systematic Review of the Literature |
| title_full | The Impact of Co-occurring Post-traumatic Stress Disorder and Substance Use Disorders on Craving: A Systematic Review of the Literature |
| title_fullStr | The Impact of Co-occurring Post-traumatic Stress Disorder and Substance Use Disorders on Craving: A Systematic Review of the Literature |
| title_full_unstemmed | The Impact of Co-occurring Post-traumatic Stress Disorder and Substance Use Disorders on Craving: A Systematic Review of the Literature |
| title_short | The Impact of Co-occurring Post-traumatic Stress Disorder and Substance Use Disorders on Craving: A Systematic Review of the Literature |
| title_sort | impact of co occurring post traumatic stress disorder and substance use disorders on craving a systematic review of the literature |
| topic | post-traumatic stress disorder (PSTD) substance use disorder dual disorder (DD) craving integrated treatment systematic (literature) review |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2021.786664/full |
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