The relationship between dietary lipophilic index and load with depression, anxiety, and stress symptoms
Abstract Background Dietary fatty acids can affect brain health by modifying neuronal membrane fluidity. Dietary lipophilic index (LI) and load (LL) may be related to cell membrane fluidity. This study aimed to determine the relationship between dietary LI and LL with symptoms of depression, anxiety...
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| Format: | Article |
| Language: | English |
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BMC
2023-09-01
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| Series: | BMC Psychiatry |
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| Online Access: | https://doi.org/10.1186/s12888-023-05161-5 |
| _version_ | 1797557395884343296 |
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| author | Mahdieh Barzegaran Shima Jazayeri Jamileh Abolghasemi Mahdieh Hosseinzadeh Seyedeh Fatemeh Fatemi Masoud Mirzaei Amin Salehi-Abargouei |
| author_facet | Mahdieh Barzegaran Shima Jazayeri Jamileh Abolghasemi Mahdieh Hosseinzadeh Seyedeh Fatemeh Fatemi Masoud Mirzaei Amin Salehi-Abargouei |
| author_sort | Mahdieh Barzegaran |
| collection | DOAJ |
| description | Abstract Background Dietary fatty acids can affect brain health by modifying neuronal membrane fluidity. Dietary lipophilic index (LI) and load (LL) may be related to cell membrane fluidity. This study aimed to determine the relationship between dietary LI and LL with symptoms of depression, anxiety and stress. Methods In this cross-sectional study, taken from the YaHS (Yazd Health Study) population-based cohort, the data of 2,982 individuals was extracted. Several questionnaires- a 178-item Food Frequency Questionnaire (FFQ), Depression, Anxiety and Stress Scale 21 (DASS 21), and International Physical Activity Questionnaire (IPAQ)- were used to obtain information on dietary intake, mental status, and physical activity, respectively. LI and LL were calculated using dietary intake and the melting point of each fatty acid. Results The analysis was performed on 2982 individuals. The odds ratio of depression in the second tertile of dietary LI compared to the first tertile was 0.815 (95% CI 0.66–1.00, P = 0.051, Ptrend = 0.017) and after adjusting confounders was 0.793 (95% CI 0.63–0.99, P = 0.043, Ptrend = 0.011). Also, LL was related inversely with anxiety (0.771, 95% CI 0.63–0.93, P = 0.003) that after multiple regression, OR of anxiety was 0.762 (95% CI 0.53–1.07, P = 0.045). The odds of stress in the third tertile of LL was 1.064 but not statistically significant (95% CI 0.88–1.28, P = 0.729). Conclusion This study showed an inverse association between dietary LI and depression symptoms. Anxiety and stress did not show a significant relationship with LI or LL. |
| first_indexed | 2024-03-10T17:16:28Z |
| format | Article |
| id | doaj.art-a038c92ca38d4a73affebd540532acdd |
| institution | Directory Open Access Journal |
| issn | 1471-244X |
| language | English |
| last_indexed | 2024-03-10T17:16:28Z |
| publishDate | 2023-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Psychiatry |
| spelling | doaj.art-a038c92ca38d4a73affebd540532acdd2023-11-20T10:29:55ZengBMCBMC Psychiatry1471-244X2023-09-012311810.1186/s12888-023-05161-5The relationship between dietary lipophilic index and load with depression, anxiety, and stress symptomsMahdieh Barzegaran0Shima Jazayeri1Jamileh Abolghasemi2Mahdieh Hosseinzadeh3Seyedeh Fatemeh Fatemi4Masoud Mirzaei5Amin Salehi-Abargouei6Department of Nutrition , School of Public Health, Iran University of Medical SciencesDepartment of Nutrition , School of Public Health, Iran University of Medical SciencesDepartment of Biostatistics, School of Public Health, Iran University of Medical SciencesDepartment of Nutrition, School of Public Health, Shahid Sadoughi University of Medical SciencesDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical SciencesYazd Cardiovascular Research Center, Non-communicable Diseases Research Institute, Shahid Sadoughi University of Medical SciencesDepartment of Nutrition, School of Public Health, Shahid Sadoughi University of Medical SciencesAbstract Background Dietary fatty acids can affect brain health by modifying neuronal membrane fluidity. Dietary lipophilic index (LI) and load (LL) may be related to cell membrane fluidity. This study aimed to determine the relationship between dietary LI and LL with symptoms of depression, anxiety and stress. Methods In this cross-sectional study, taken from the YaHS (Yazd Health Study) population-based cohort, the data of 2,982 individuals was extracted. Several questionnaires- a 178-item Food Frequency Questionnaire (FFQ), Depression, Anxiety and Stress Scale 21 (DASS 21), and International Physical Activity Questionnaire (IPAQ)- were used to obtain information on dietary intake, mental status, and physical activity, respectively. LI and LL were calculated using dietary intake and the melting point of each fatty acid. Results The analysis was performed on 2982 individuals. The odds ratio of depression in the second tertile of dietary LI compared to the first tertile was 0.815 (95% CI 0.66–1.00, P = 0.051, Ptrend = 0.017) and after adjusting confounders was 0.793 (95% CI 0.63–0.99, P = 0.043, Ptrend = 0.011). Also, LL was related inversely with anxiety (0.771, 95% CI 0.63–0.93, P = 0.003) that after multiple regression, OR of anxiety was 0.762 (95% CI 0.53–1.07, P = 0.045). The odds of stress in the third tertile of LL was 1.064 but not statistically significant (95% CI 0.88–1.28, P = 0.729). Conclusion This study showed an inverse association between dietary LI and depression symptoms. Anxiety and stress did not show a significant relationship with LI or LL.https://doi.org/10.1186/s12888-023-05161-5Lipophilic indexLipophilic loadDepressionAnxietyStress |
| spellingShingle | Mahdieh Barzegaran Shima Jazayeri Jamileh Abolghasemi Mahdieh Hosseinzadeh Seyedeh Fatemeh Fatemi Masoud Mirzaei Amin Salehi-Abargouei The relationship between dietary lipophilic index and load with depression, anxiety, and stress symptoms BMC Psychiatry Lipophilic index Lipophilic load Depression Anxiety Stress |
| title | The relationship between dietary lipophilic index and load with depression, anxiety, and stress symptoms |
| title_full | The relationship between dietary lipophilic index and load with depression, anxiety, and stress symptoms |
| title_fullStr | The relationship between dietary lipophilic index and load with depression, anxiety, and stress symptoms |
| title_full_unstemmed | The relationship between dietary lipophilic index and load with depression, anxiety, and stress symptoms |
| title_short | The relationship between dietary lipophilic index and load with depression, anxiety, and stress symptoms |
| title_sort | relationship between dietary lipophilic index and load with depression anxiety and stress symptoms |
| topic | Lipophilic index Lipophilic load Depression Anxiety Stress |
| url | https://doi.org/10.1186/s12888-023-05161-5 |
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