Transcriptomic effects of propranolol and primidone converge on molecular pathways relevant to essential tremor

Abstract Essential tremor (ET) is one of the most common movement disorders, affecting nearly 5% of individuals over 65 years old. Despite this, few genetic risk loci for ET have been identified. Recent advances in pharmacogenomics have previously been useful to identify disease related molecular ta...

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Bibliographic Details
Main Authors: Charles-Etienne Castonguay, Calwing Liao, Anouar Khayachi, Yumin Liu, Miranda Medeiros, Gabrielle Houle, Jay P. Ross, Patrick A. Dion, Guy A. Rouleau
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:npj Genomic Medicine
Online Access:https://doi.org/10.1038/s41525-022-00318-9