Novel Mg-Incorporated Micro-Arc Oxidation Coatings for Orthopedic Implants Application
In this study, Ti-6Al-4V alloy samples were processed by micro-arc oxidation (MAO) in phytic acid (H<sub>12</sub>Phy) electrolytes with the addition of different concentrations of EDTA-MgNa<sub>2</sub> (Na<sub>2</sub>MgY) and potassium hydroxide (KOH). The surface...
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| author | Rongfa Zhang Sheng Zhong Lilan Zeng Hongyu Li Rongfang Zhao Shufang Zhang Xinting Duan Jingsong Huang Ying Zhao |
| author_facet | Rongfa Zhang Sheng Zhong Lilan Zeng Hongyu Li Rongfang Zhao Shufang Zhang Xinting Duan Jingsong Huang Ying Zhao |
| author_sort | Rongfa Zhang |
| collection | DOAJ |
| description | In this study, Ti-6Al-4V alloy samples were processed by micro-arc oxidation (MAO) in phytic acid (H<sub>12</sub>Phy) electrolytes with the addition of different concentrations of EDTA-MgNa<sub>2</sub> (Na<sub>2</sub>MgY) and potassium hydroxide (KOH). The surface characterization and cytocompatibility of MAO-treated samples were evaluated systematically. H<sub>12</sub>Phy is a necessary agent for MAO coating formation, and the addition of Na<sub>2</sub>MgY and KOH into the electrolytes increases the surface roughness, micropore size and Mg contents in the coatings. The MAO coatings are primarily composed of anatase, rutile, MgO and Mg<sub>3</sub>(PO<sub>4</sub>)<sub>2</sub>. Magnesium (Mg) ions in the electrolytes enter into MAO coatings by diffusion and electromigration. The MAO coatings containing 2.97 at% Mg show excellent cell viability, adhesion, proliferation, alkaline phosphatase activity, extracellular matrix (ECM) mineralization and collagen secretion, but the cytocompatibility of the MAO coatings containing 6.82 at% Mg was the worst due to the excessively high Mg content. Our results revealed that MAO coatings with proper Mg contents improve the cytocompatibility of the Ti-6Al-4V alloys and have large potential in orthopedic applications. |
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| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-10T06:56:13Z |
| publishDate | 2021-09-01 |
| publisher | MDPI AG |
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| series | Materials |
| spelling | doaj.art-a03a662a4ecc49ebaa6382098b11e3ab2023-11-22T16:25:50ZengMDPI AGMaterials1996-19442021-09-011419571010.3390/ma14195710Novel Mg-Incorporated Micro-Arc Oxidation Coatings for Orthopedic Implants ApplicationRongfa Zhang0Sheng Zhong1Lilan Zeng2Hongyu Li3Rongfang Zhao4Shufang Zhang5Xinting Duan6Jingsong Huang7Ying Zhao8School of Materials and Electromechanics, Jiangxi Science and Technology Normal University, Nanchang 330038, ChinaSchool of Materials and Electromechanics, Jiangxi Science and Technology Normal University, Nanchang 330038, ChinaShenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, ChinaShenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, ChinaSchool of Materials and Electromechanics, Jiangxi Science and Technology Normal University, Nanchang 330038, ChinaSchool of Materials and Electromechanics, Jiangxi Science and Technology Normal University, Nanchang 330038, ChinaSchool of Materials and Electromechanics, Jiangxi Science and Technology Normal University, Nanchang 330038, ChinaSchool of Materials and Electromechanics, Jiangxi Science and Technology Normal University, Nanchang 330038, ChinaShenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, ChinaIn this study, Ti-6Al-4V alloy samples were processed by micro-arc oxidation (MAO) in phytic acid (H<sub>12</sub>Phy) electrolytes with the addition of different concentrations of EDTA-MgNa<sub>2</sub> (Na<sub>2</sub>MgY) and potassium hydroxide (KOH). The surface characterization and cytocompatibility of MAO-treated samples were evaluated systematically. H<sub>12</sub>Phy is a necessary agent for MAO coating formation, and the addition of Na<sub>2</sub>MgY and KOH into the electrolytes increases the surface roughness, micropore size and Mg contents in the coatings. The MAO coatings are primarily composed of anatase, rutile, MgO and Mg<sub>3</sub>(PO<sub>4</sub>)<sub>2</sub>. Magnesium (Mg) ions in the electrolytes enter into MAO coatings by diffusion and electromigration. The MAO coatings containing 2.97 at% Mg show excellent cell viability, adhesion, proliferation, alkaline phosphatase activity, extracellular matrix (ECM) mineralization and collagen secretion, but the cytocompatibility of the MAO coatings containing 6.82 at% Mg was the worst due to the excessively high Mg content. Our results revealed that MAO coatings with proper Mg contents improve the cytocompatibility of the Ti-6Al-4V alloys and have large potential in orthopedic applications.https://www.mdpi.com/1996-1944/14/19/5710titanium alloysmicro-arc oxidationcytocompatibilitymagnesiumH<sub>12</sub>Phy |
| spellingShingle | Rongfa Zhang Sheng Zhong Lilan Zeng Hongyu Li Rongfang Zhao Shufang Zhang Xinting Duan Jingsong Huang Ying Zhao Novel Mg-Incorporated Micro-Arc Oxidation Coatings for Orthopedic Implants Application Materials titanium alloys micro-arc oxidation cytocompatibility magnesium H<sub>12</sub>Phy |
| title | Novel Mg-Incorporated Micro-Arc Oxidation Coatings for Orthopedic Implants Application |
| title_full | Novel Mg-Incorporated Micro-Arc Oxidation Coatings for Orthopedic Implants Application |
| title_fullStr | Novel Mg-Incorporated Micro-Arc Oxidation Coatings for Orthopedic Implants Application |
| title_full_unstemmed | Novel Mg-Incorporated Micro-Arc Oxidation Coatings for Orthopedic Implants Application |
| title_short | Novel Mg-Incorporated Micro-Arc Oxidation Coatings for Orthopedic Implants Application |
| title_sort | novel mg incorporated micro arc oxidation coatings for orthopedic implants application |
| topic | titanium alloys micro-arc oxidation cytocompatibility magnesium H<sub>12</sub>Phy |
| url | https://www.mdpi.com/1996-1944/14/19/5710 |
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