Pharmacological evidence for the possible involvement of the NMDA receptor pathway in the anticonvulsant effect of tramadol in mice

Pharmacological evidence for the possible involvement of the NMDA receptor pathway in the anticonvulsant effect of tramadol in mice

Background: Previous studies have shown controversial results regarding the pro- or anticonvulsant effects of tramadol. Additionally, the underlying mechanism of seizure induction or alleviation by tramadol has not been fully understood. In the current study, the effects of tramadol on pentylenetet...

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Bibliographic Details
Main Authors: Mazyar Zahir, Amir Rashidian, Mohsen Hoseini, Reyhaneh Akbarian, Mohsen Chamanara
Format: Article
Language:English
Published: AIMS Press 2022-11-01
Series:AIMS Neuroscience
Subjects:
anticonvulsants
mice
n-methylaspartate
seizures
tramadol
Online Access:https://www.aimspress.com/article/doi/10.3934/Neuroscience.2022024?viewType=HTML

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