Novel kinome profiling technology reveals drug treatment is patient and 2D/3D model dependent in glioblastoma
Glioblastoma is the deadliest brain cancer. One of the main reasons for poor outcome resides in therapy resistance, which adds additional challenges in finding an effective treatment. Small protein kinase inhibitors are molecules that have become widely studied for cancer treatments, including gliob...
Main Authors: | Federica Fabro, Nynke M. Kannegieter, Erik L. de Graaf, Karla Queiroz, Martine L. M. Lamfers, Anna Ressa, Sieger Leenstra |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-11-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2022.1012236/full |
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