Quantification of cell migration: metrics selection to model application
Cell migration plays an essential role in physiological and pathological states, such as immune response, tissue generation and tumor development. This phenomenon can occur spontaneously or it can be triggered by an external stimuli, including biochemical, mechanical, or electrical cues that induce...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Cell and Developmental Biology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2023.1155882/full |
| _version_ | 1797826855068237824 |
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| author | Yang Hu Matthew L. Becker Rebecca Kuntz Willits Rebecca Kuntz Willits |
| author_facet | Yang Hu Matthew L. Becker Rebecca Kuntz Willits Rebecca Kuntz Willits |
| author_sort | Yang Hu |
| collection | DOAJ |
| description | Cell migration plays an essential role in physiological and pathological states, such as immune response, tissue generation and tumor development. This phenomenon can occur spontaneously or it can be triggered by an external stimuli, including biochemical, mechanical, or electrical cues that induce or direct cells to migrate. The migratory response to these cues is foundational to several fields including neuroscience, cancer and regenerative medicine. Various platforms are available to qualitatively and quantitatively measure cell migration, making the measurements of cell motility straight-forward. Migratory behavior must be analyzed by multiple metrics and then models to connect the measurements to physiological meaning. This review will focus on describing and quantifying cell movement for individual cell migration. |
| first_indexed | 2024-04-09T12:40:01Z |
| format | Article |
| id | doaj.art-a03fbf4ad5d74db991ec427262652223 |
| institution | Directory Open Access Journal |
| issn | 2296-634X |
| language | English |
| last_indexed | 2024-04-09T12:40:01Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cell and Developmental Biology |
| spelling | doaj.art-a03fbf4ad5d74db991ec4272626522232023-05-15T04:32:39ZengFrontiers Media S.A.Frontiers in Cell and Developmental Biology2296-634X2023-05-011110.3389/fcell.2023.11558821155882Quantification of cell migration: metrics selection to model applicationYang Hu0Matthew L. Becker1Rebecca Kuntz Willits2Rebecca Kuntz Willits3Department of Chemical Engineering, College of Engineering, Northeastern University, Boston, MA, United StatesDepartments of Chemistry, Mechanical Engineering and Materials Science, Biomedical Engineering and Orthopedic Surgery, Duke University, Durham, NC, United StatesDepartment of Chemical Engineering, College of Engineering, Northeastern University, Boston, MA, United StatesDepartment of Bioengineering, College of Engineering, Northeastern University, Boston, MA, United StatesCell migration plays an essential role in physiological and pathological states, such as immune response, tissue generation and tumor development. This phenomenon can occur spontaneously or it can be triggered by an external stimuli, including biochemical, mechanical, or electrical cues that induce or direct cells to migrate. The migratory response to these cues is foundational to several fields including neuroscience, cancer and regenerative medicine. Various platforms are available to qualitatively and quantitatively measure cell migration, making the measurements of cell motility straight-forward. Migratory behavior must be analyzed by multiple metrics and then models to connect the measurements to physiological meaning. This review will focus on describing and quantifying cell movement for individual cell migration.https://www.frontiersin.org/articles/10.3389/fcell.2023.1155882/fullindividual cell migrationdiffusionbrowniananamolous diffusioncell motility analysis |
| spellingShingle | Yang Hu Matthew L. Becker Rebecca Kuntz Willits Rebecca Kuntz Willits Quantification of cell migration: metrics selection to model application Frontiers in Cell and Developmental Biology individual cell migration diffusion brownian anamolous diffusion cell motility analysis |
| title | Quantification of cell migration: metrics selection to model application |
| title_full | Quantification of cell migration: metrics selection to model application |
| title_fullStr | Quantification of cell migration: metrics selection to model application |
| title_full_unstemmed | Quantification of cell migration: metrics selection to model application |
| title_short | Quantification of cell migration: metrics selection to model application |
| title_sort | quantification of cell migration metrics selection to model application |
| topic | individual cell migration diffusion brownian anamolous diffusion cell motility analysis |
| url | https://www.frontiersin.org/articles/10.3389/fcell.2023.1155882/full |
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