Recent Findings in Azaphilone Pigments
Filamentous fungi are known to biosynthesize an extraordinary range of azaphilones pigments with structural diversity and advantages over vegetal-derived colored natural products such agile and simple cultivation in the lab, acceptance of low-cost substrates, speed yield improvement, and ease of dow...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-07-01
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| Series: | Journal of Fungi |
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| Online Access: | https://www.mdpi.com/2309-608X/7/7/541 |
| _version_ | 1797526806549495808 |
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| author | Lúcia P. S. Pimenta Dhionne C. Gomes Patrícia G. Cardoso Jacqueline A. Takahashi |
| author_facet | Lúcia P. S. Pimenta Dhionne C. Gomes Patrícia G. Cardoso Jacqueline A. Takahashi |
| author_sort | Lúcia P. S. Pimenta |
| collection | DOAJ |
| description | Filamentous fungi are known to biosynthesize an extraordinary range of azaphilones pigments with structural diversity and advantages over vegetal-derived colored natural products such agile and simple cultivation in the lab, acceptance of low-cost substrates, speed yield improvement, and ease of downstream processing. Modern genetic engineering allows industrial production, providing pigments with higher thermostability, water-solubility, and promising bioactivities combined with ecological functions. This review, covering the literature from 2020 onwards, focuses on the state-of-the-art of azaphilone dyes, the global market scenario, new compounds isolated in the period with respective biological activities, and biosynthetic pathways. Furthermore, we discussed the innovations of azaphilone cultivation and extraction techniques, as well as in yield improvement and scale-up. Potential applications in the food, cosmetic, pharmaceutical, and textile industries were also explored. |
| first_indexed | 2024-03-10T09:35:32Z |
| format | Article |
| id | doaj.art-a03fe18d5f604eb5affd5ceff35fc950 |
| institution | Directory Open Access Journal |
| issn | 2309-608X |
| language | English |
| last_indexed | 2024-03-10T09:35:32Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Fungi |
| spelling | doaj.art-a03fe18d5f604eb5affd5ceff35fc9502023-11-22T04:09:48ZengMDPI AGJournal of Fungi2309-608X2021-07-017754110.3390/jof7070541Recent Findings in Azaphilone PigmentsLúcia P. S. Pimenta0Dhionne C. Gomes1Patrícia G. Cardoso2Jacqueline A. Takahashi3Department of Chemistry, Universidade Federal de Minas Gerais (UFMG), Av. Antonio Carlos, 6627, Belo Horizonte CEP 31270-901, MG, BrazilDepartment of Food Science, Universidade Federal de Minas Gerais (UFMG), Av. Antonio Carlos, 6627, Belo Horizonte CEP 31270-901, MG, BrazilDepartment of Biology, Universidade Federal de Lavras, Av. Dr. Sylvio Menicucci, 1001, Lavras CEP 37200-900, MG, BrazilDepartment of Chemistry, Universidade Federal de Minas Gerais (UFMG), Av. Antonio Carlos, 6627, Belo Horizonte CEP 31270-901, MG, BrazilFilamentous fungi are known to biosynthesize an extraordinary range of azaphilones pigments with structural diversity and advantages over vegetal-derived colored natural products such agile and simple cultivation in the lab, acceptance of low-cost substrates, speed yield improvement, and ease of downstream processing. Modern genetic engineering allows industrial production, providing pigments with higher thermostability, water-solubility, and promising bioactivities combined with ecological functions. This review, covering the literature from 2020 onwards, focuses on the state-of-the-art of azaphilone dyes, the global market scenario, new compounds isolated in the period with respective biological activities, and biosynthetic pathways. Furthermore, we discussed the innovations of azaphilone cultivation and extraction techniques, as well as in yield improvement and scale-up. Potential applications in the food, cosmetic, pharmaceutical, and textile industries were also explored.https://www.mdpi.com/2309-608X/7/7/541natural pigmentsfilamentous fungiazaphilonesproductionbiotechnological toolsnon-mycotoxigenic strains |
| spellingShingle | Lúcia P. S. Pimenta Dhionne C. Gomes Patrícia G. Cardoso Jacqueline A. Takahashi Recent Findings in Azaphilone Pigments Journal of Fungi natural pigments filamentous fungi azaphilones production biotechnological tools non-mycotoxigenic strains |
| title | Recent Findings in Azaphilone Pigments |
| title_full | Recent Findings in Azaphilone Pigments |
| title_fullStr | Recent Findings in Azaphilone Pigments |
| title_full_unstemmed | Recent Findings in Azaphilone Pigments |
| title_short | Recent Findings in Azaphilone Pigments |
| title_sort | recent findings in azaphilone pigments |
| topic | natural pigments filamentous fungi azaphilones production biotechnological tools non-mycotoxigenic strains |
| url | https://www.mdpi.com/2309-608X/7/7/541 |
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