Enhancement of bioactive compounds and biological activities of Centella asiatica through ultrasound treatment
Centella asiatica possess various health-promoting activities owing to its bioactive compounds such as triterpenes, flavonoids, and vitamins. Ultrasound treatment during the post-harvest process is a good strategy for eliciting secondary metabolite in plants. The present study investigated the effec...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-03-01
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| Series: | Ultrasonics Sonochemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1350417723000652 |
| _version_ | 1797867676919398400 |
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| author | Eunjeong Seong Huijin Heo Heon Sang Jeong Hana Lee Junsoo Lee |
| author_facet | Eunjeong Seong Huijin Heo Heon Sang Jeong Hana Lee Junsoo Lee |
| author_sort | Eunjeong Seong |
| collection | DOAJ |
| description | Centella asiatica possess various health-promoting activities owing to its bioactive compounds such as triterpenes, flavonoids, and vitamins. Ultrasound treatment during the post-harvest process is a good strategy for eliciting secondary metabolite in plants. The present study investigated the effect of ultrasound treatment for different time durations on the bioactive compounds and biological activities of C. asiatica leaves. The leaves were treated with ultrasound for 5, 10, and 20 min. Ultrasound elicitation (especially for 10 min) markedly elevated the accumulation of stress markers, leading to enhanced phenolic-triggering enzyme activities. The accumulation of secondary metabolites and antioxidant activities were also significantly improved compared with that in untreated leaves. In addition, ultrasound-treated C. asiatica leaves protected myoblasts against H2O2-induced oxidative stress by regulating reactive oxygen species production, glutathione depletion, and lipid peroxidation. These findings indicate that elicitation using ultrasound can be a simple method for increasing functional compound production and enhancing biological activities in C. asiatica leaves. |
| first_indexed | 2024-04-09T23:43:58Z |
| format | Article |
| id | doaj.art-a04535f9205244178370b27db97d9795 |
| institution | Directory Open Access Journal |
| issn | 1350-4177 |
| language | English |
| last_indexed | 2024-04-09T23:43:58Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Ultrasonics Sonochemistry |
| spelling | doaj.art-a04535f9205244178370b27db97d97952023-03-18T04:40:40ZengElsevierUltrasonics Sonochemistry1350-41772023-03-0194106353Enhancement of bioactive compounds and biological activities of Centella asiatica through ultrasound treatmentEunjeong Seong0Huijin Heo1Heon Sang Jeong2Hana Lee3Junsoo Lee4Department of Food Science and Biotechnology, Chungbuk National University, Cheongju, Chungbuk 28644, KoreaDepartment of Food Science and Biotechnology, Chungbuk National University, Cheongju, Chungbuk 28644, KoreaDepartment of Food Science and Biotechnology, Chungbuk National University, Cheongju, Chungbuk 28644, KoreaCorresponding authors at: Department of Food Science and Biotechnology, College of Agriculture, Life, & Environmental Sciences, Chungbuk National University, 1 Chungdae-ro, Seowon-gu, Cheongju, Chungbuk 28644, Korea.; Department of Food Science and Biotechnology, Chungbuk National University, Cheongju, Chungbuk 28644, KoreaCorresponding authors at: Department of Food Science and Biotechnology, College of Agriculture, Life, & Environmental Sciences, Chungbuk National University, 1 Chungdae-ro, Seowon-gu, Cheongju, Chungbuk 28644, Korea.; Department of Food Science and Biotechnology, Chungbuk National University, Cheongju, Chungbuk 28644, KoreaCentella asiatica possess various health-promoting activities owing to its bioactive compounds such as triterpenes, flavonoids, and vitamins. Ultrasound treatment during the post-harvest process is a good strategy for eliciting secondary metabolite in plants. The present study investigated the effect of ultrasound treatment for different time durations on the bioactive compounds and biological activities of C. asiatica leaves. The leaves were treated with ultrasound for 5, 10, and 20 min. Ultrasound elicitation (especially for 10 min) markedly elevated the accumulation of stress markers, leading to enhanced phenolic-triggering enzyme activities. The accumulation of secondary metabolites and antioxidant activities were also significantly improved compared with that in untreated leaves. In addition, ultrasound-treated C. asiatica leaves protected myoblasts against H2O2-induced oxidative stress by regulating reactive oxygen species production, glutathione depletion, and lipid peroxidation. These findings indicate that elicitation using ultrasound can be a simple method for increasing functional compound production and enhancing biological activities in C. asiatica leaves.http://www.sciencedirect.com/science/article/pii/S1350417723000652UltrasoundPost-harvest treatmentCentella asiaticaElicitationMyoblasts |
| spellingShingle | Eunjeong Seong Huijin Heo Heon Sang Jeong Hana Lee Junsoo Lee Enhancement of bioactive compounds and biological activities of Centella asiatica through ultrasound treatment Ultrasonics Sonochemistry Ultrasound Post-harvest treatment Centella asiatica Elicitation Myoblasts |
| title | Enhancement of bioactive compounds and biological activities of Centella asiatica through ultrasound treatment |
| title_full | Enhancement of bioactive compounds and biological activities of Centella asiatica through ultrasound treatment |
| title_fullStr | Enhancement of bioactive compounds and biological activities of Centella asiatica through ultrasound treatment |
| title_full_unstemmed | Enhancement of bioactive compounds and biological activities of Centella asiatica through ultrasound treatment |
| title_short | Enhancement of bioactive compounds and biological activities of Centella asiatica through ultrasound treatment |
| title_sort | enhancement of bioactive compounds and biological activities of centella asiatica through ultrasound treatment |
| topic | Ultrasound Post-harvest treatment Centella asiatica Elicitation Myoblasts |
| url | http://www.sciencedirect.com/science/article/pii/S1350417723000652 |
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