Study on Motion Management of Pancreatic Cancer Treated by CyberKnife
PurposeWe investigated the movement characteristics of pancreas and the clinical accuracy of tracking pancreas with the Synchrony Respiratory Tracking System (SRTS) during the CyberKnife treatment. These data provide a clinical data basis for the expansion margins of pancreatic tumor target.Methods...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-12-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2021.767832/full |
| _version_ | 1818844166331826176 |
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| author | Shenghua Jing Changchen Jiang Xiaoqin Ji Xiangnan Qiu Jing Li Xiangdong Sun Xixu Zhu |
| author_facet | Shenghua Jing Changchen Jiang Xiaoqin Ji Xiangnan Qiu Jing Li Xiangdong Sun Xixu Zhu |
| author_sort | Shenghua Jing |
| collection | DOAJ |
| description | PurposeWe investigated the movement characteristics of pancreas and the clinical accuracy of tracking pancreas with the Synchrony Respiratory Tracking System (SRTS) during the CyberKnife treatment. These data provide a clinical data basis for the expansion margins of pancreatic tumor target.Methods and MaterialsForty-two patients with pancreatic cancer treated by CyberKnife were retrospectively studied. The pancreatic displacement calculated from the x-ray images collected during the time interval between two consecutive movements constituted a data set.ResultsThe total mean motion amplitudes and standard deviations of pancreatic tumors in SI, LR, AP, and radial directions were 3.66 ± 1.71 mm, 0.97 ± 0.62 mm, 1.52 ± 1.02 mm, and 1.36 ± 0.49 mm, respectively. The overall mean correlation errors and standard deviations were 0.82 ± 0.46 mm, 0.47 ± 0.33 mm, 0.41 ± 0.24 mm, and 0.98 ± 0.37 mm, respectively. The overall mean prediction errors and standard deviations were 0.57 ± 0.14 mm, 0.62 ± 0.28 mm, 0.39 ± 0.17 mm, and 1.58 ± 0.36 mm, respectively. The correlation errors and prediction errors of pancreatic tumors at different anatomical positions in SI, LR, and AP directions were statistically significant (p < 0.05).ConclusionsThe tumor motion amplitude, the tumor location, and the treatment time are the main factors affecting the tracking accuracy. The pancreatic tumors at different anatomical locations should be treated differently to ensure sufficient dose coverage of the pancreatic target area. |
| first_indexed | 2024-12-19T05:09:26Z |
| format | Article |
| id | doaj.art-a04956752a444bc5a54ef18f9a44caee |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-12-19T05:09:26Z |
| publishDate | 2021-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-a04956752a444bc5a54ef18f9a44caee2022-12-21T20:34:51ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2021-12-011110.3389/fonc.2021.767832767832Study on Motion Management of Pancreatic Cancer Treated by CyberKnifeShenghua JingChangchen JiangXiaoqin JiXiangnan QiuJing LiXiangdong SunXixu ZhuPurposeWe investigated the movement characteristics of pancreas and the clinical accuracy of tracking pancreas with the Synchrony Respiratory Tracking System (SRTS) during the CyberKnife treatment. These data provide a clinical data basis for the expansion margins of pancreatic tumor target.Methods and MaterialsForty-two patients with pancreatic cancer treated by CyberKnife were retrospectively studied. The pancreatic displacement calculated from the x-ray images collected during the time interval between two consecutive movements constituted a data set.ResultsThe total mean motion amplitudes and standard deviations of pancreatic tumors in SI, LR, AP, and radial directions were 3.66 ± 1.71 mm, 0.97 ± 0.62 mm, 1.52 ± 1.02 mm, and 1.36 ± 0.49 mm, respectively. The overall mean correlation errors and standard deviations were 0.82 ± 0.46 mm, 0.47 ± 0.33 mm, 0.41 ± 0.24 mm, and 0.98 ± 0.37 mm, respectively. The overall mean prediction errors and standard deviations were 0.57 ± 0.14 mm, 0.62 ± 0.28 mm, 0.39 ± 0.17 mm, and 1.58 ± 0.36 mm, respectively. The correlation errors and prediction errors of pancreatic tumors at different anatomical positions in SI, LR, and AP directions were statistically significant (p < 0.05).ConclusionsThe tumor motion amplitude, the tumor location, and the treatment time are the main factors affecting the tracking accuracy. The pancreatic tumors at different anatomical locations should be treated differently to ensure sufficient dose coverage of the pancreatic target area.https://www.frontiersin.org/articles/10.3389/fonc.2021.767832/fullCyberKnifeexpansion marginpancreatic cancerSRTStumor motion management |
| spellingShingle | Shenghua Jing Changchen Jiang Xiaoqin Ji Xiangnan Qiu Jing Li Xiangdong Sun Xixu Zhu Study on Motion Management of Pancreatic Cancer Treated by CyberKnife Frontiers in Oncology CyberKnife expansion margin pancreatic cancer SRTS tumor motion management |
| title | Study on Motion Management of Pancreatic Cancer Treated by CyberKnife |
| title_full | Study on Motion Management of Pancreatic Cancer Treated by CyberKnife |
| title_fullStr | Study on Motion Management of Pancreatic Cancer Treated by CyberKnife |
| title_full_unstemmed | Study on Motion Management of Pancreatic Cancer Treated by CyberKnife |
| title_short | Study on Motion Management of Pancreatic Cancer Treated by CyberKnife |
| title_sort | study on motion management of pancreatic cancer treated by cyberknife |
| topic | CyberKnife expansion margin pancreatic cancer SRTS tumor motion management |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2021.767832/full |
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