Surviving a decade or more after coronary revascularization in a middle Eastern population: The impact of diabetes mellitus
Introduction: Studies that evaluate Middle Eastern patients who have long-term survival after coronary artery revascularization are scarce. The prevalence of diabetes mellitus (DM) is high and rapidly increasing in our region. Methods: The study enrolled consecutive ambulatory or in-patients who had...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Heart Views |
| Subjects: | |
| Online Access: | http://www.heartviews.org/article.asp?issn=1995-705X;year=2022;volume=23;issue=2;spage=73;epage=77;aulast=Alhaddad |
| _version_ | 1811343823277654016 |
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| author | Imad A Alhaddad Ramzi Tabbalat Yousef Khader Zaid Elkarmi Zaid Dahabreh Ayman Hammoudeh |
| author_facet | Imad A Alhaddad Ramzi Tabbalat Yousef Khader Zaid Elkarmi Zaid Dahabreh Ayman Hammoudeh |
| author_sort | Imad A Alhaddad |
| collection | DOAJ |
| description | Introduction: Studies that evaluate Middle Eastern patients who have long-term survival after coronary artery revascularization are scarce. The prevalence of diabetes mellitus (DM) is high and rapidly increasing in our region.
Methods: The study enrolled consecutive ambulatory or in-patients who had percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) surgery at least 10 years earlier. Collected data included cardiovascular risk factors at the time of the index revascularization and evolution of risk factors since then, the occurrence of cardiovascular events, and the need for coronary revascularization after the index procedure. Events were compared between patients with DM and no DM at baseline.
Results: The study population consisted of 891 consecutive patients with 351 patients (39.4%) had DM and 540 patients (60.6%) had no DM. The mean age at baseline was 53.9 ± 8.8 years for DM patients and 53.0 ± 9.8 years for no DM patients (P = 0.16). At baseline, the DM group had more hypertension (70.9% vs. 27.6%, P < 0.0001), more dyslipidemias (12% vs. 5.2%, P = 0.001) but less smokers compared to no DM group (44.4% vs. 58.3%, P < 0.001). DM and no DM groups had similar proportion of PCI (65.5% vs. 68.3%, P = 0.42) and CABG (34.5% vs. 31.7%, P = 0.43) at baseline. Following the index revascularization procedure, acute coronary events, heart failure, and stroke developed in similar proportions in the two groups. Repeat revascularization after the index procedure showed that the DM group had more PCI compared to no DM group (52.7% vs. 45.4%, P = 0.04) but similar proportions of CABG (7.1% vs. 9.8%, P = 0.20).
Conclusions: In this retrospective observation of Middle Eastern patients who survived at least a decade after coronary revascularization, the DM group had more hypertension and dyslipidemias but fewer smokers compared to no DM at baseline. During follow-up, the DM group required more PCI revascularization compared with no DM group. |
| first_indexed | 2024-04-13T19:35:42Z |
| format | Article |
| id | doaj.art-a04a145f83ec45f285a5a2bd09121477 |
| institution | Directory Open Access Journal |
| issn | 1995-705X |
| language | English |
| last_indexed | 2024-04-13T19:35:42Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Heart Views |
| spelling | doaj.art-a04a145f83ec45f285a5a2bd091214772022-12-22T02:33:02ZengWolters Kluwer Medknow PublicationsHeart Views1995-705X2022-01-01232737710.4103/HEARTVIEWS.HEARTVIEWS_36_21Surviving a decade or more after coronary revascularization in a middle Eastern population: The impact of diabetes mellitusImad A AlhaddadRamzi TabbalatYousef KhaderZaid ElkarmiZaid DahabrehAyman HammoudehIntroduction: Studies that evaluate Middle Eastern patients who have long-term survival after coronary artery revascularization are scarce. The prevalence of diabetes mellitus (DM) is high and rapidly increasing in our region. Methods: The study enrolled consecutive ambulatory or in-patients who had percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) surgery at least 10 years earlier. Collected data included cardiovascular risk factors at the time of the index revascularization and evolution of risk factors since then, the occurrence of cardiovascular events, and the need for coronary revascularization after the index procedure. Events were compared between patients with DM and no DM at baseline. Results: The study population consisted of 891 consecutive patients with 351 patients (39.4%) had DM and 540 patients (60.6%) had no DM. The mean age at baseline was 53.9 ± 8.8 years for DM patients and 53.0 ± 9.8 years for no DM patients (P = 0.16). At baseline, the DM group had more hypertension (70.9% vs. 27.6%, P < 0.0001), more dyslipidemias (12% vs. 5.2%, P = 0.001) but less smokers compared to no DM group (44.4% vs. 58.3%, P < 0.001). DM and no DM groups had similar proportion of PCI (65.5% vs. 68.3%, P = 0.42) and CABG (34.5% vs. 31.7%, P = 0.43) at baseline. Following the index revascularization procedure, acute coronary events, heart failure, and stroke developed in similar proportions in the two groups. Repeat revascularization after the index procedure showed that the DM group had more PCI compared to no DM group (52.7% vs. 45.4%, P = 0.04) but similar proportions of CABG (7.1% vs. 9.8%, P = 0.20). Conclusions: In this retrospective observation of Middle Eastern patients who survived at least a decade after coronary revascularization, the DM group had more hypertension and dyslipidemias but fewer smokers compared to no DM at baseline. During follow-up, the DM group required more PCI revascularization compared with no DM group.http://www.heartviews.org/article.asp?issn=1995-705X;year=2022;volume=23;issue=2;spage=73;epage=77;aulast=Alhaddadcoronary artery bypass graft surgerycoronary revascularizationdiabetes mellituslong-term survivalmiddle eastpercutaneous coronary intervention |
| spellingShingle | Imad A Alhaddad Ramzi Tabbalat Yousef Khader Zaid Elkarmi Zaid Dahabreh Ayman Hammoudeh Surviving a decade or more after coronary revascularization in a middle Eastern population: The impact of diabetes mellitus Heart Views coronary artery bypass graft surgery coronary revascularization diabetes mellitus long-term survival middle east percutaneous coronary intervention |
| title | Surviving a decade or more after coronary revascularization in a middle Eastern population: The impact of diabetes mellitus |
| title_full | Surviving a decade or more after coronary revascularization in a middle Eastern population: The impact of diabetes mellitus |
| title_fullStr | Surviving a decade or more after coronary revascularization in a middle Eastern population: The impact of diabetes mellitus |
| title_full_unstemmed | Surviving a decade or more after coronary revascularization in a middle Eastern population: The impact of diabetes mellitus |
| title_short | Surviving a decade or more after coronary revascularization in a middle Eastern population: The impact of diabetes mellitus |
| title_sort | surviving a decade or more after coronary revascularization in a middle eastern population the impact of diabetes mellitus |
| topic | coronary artery bypass graft surgery coronary revascularization diabetes mellitus long-term survival middle east percutaneous coronary intervention |
| url | http://www.heartviews.org/article.asp?issn=1995-705X;year=2022;volume=23;issue=2;spage=73;epage=77;aulast=Alhaddad |
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