Level of constitutively expressed BMAL1 affects the robustness of circadian oscillations

Abstract The circadian rhythm is a biological oscillation of physiological activities with a period of approximately 24 h, that is driven by a cell-autonomous oscillator called the circadian clock. The current model of the mammalian circadian clock is based on a transcriptional-translational negativ...

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Bibliographic Details
Main Authors: Apirada Padlom, Daisuke Ono, Rio Hamashima, Yuko Furukawa, Takashi Yoshimura, Taeko Nishiwaki-Ohkawa
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-24188-4