Case Report: Exploration of changes in serum immunoinflammation-related protein complexes of patients with metastatic breast cancer

Patients with advanced breast cancer are difficult to treat and have poor prognosis. At present, the commonly used methods to monitor the disease progression of breast cancer are imaging examinations such as breast ultrasound, mammography and peripheral blood tumor markers such as carcinoembryonic a...

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Main Authors: Chang Chen, Yali Xu, Zhizhen Lai, Zhili Li, Qiang Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1207991/full
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author Chang Chen
Yali Xu
Zhizhen Lai
Zhili Li
Qiang Sun
author_facet Chang Chen
Yali Xu
Zhizhen Lai
Zhili Li
Qiang Sun
author_sort Chang Chen
collection DOAJ
description Patients with advanced breast cancer are difficult to treat and have poor prognosis. At present, the commonly used methods to monitor the disease progression of breast cancer are imaging examinations such as breast ultrasound, mammography and peripheral blood tumor markers such as carcinoembryonic antigen (CEA) and carbohydrate antigen 15-3 (CA15-3). However, none of them can detect tumor progression at an early stage. Serum immunoinflammation-related protein complexes (IIRPCs) showed potential to indicate cancer progression. Therefore, we attempted to monitor the level of IIRPCs in peripheral blood of patients with metastatic breast cancer and compare it with patients’ treatment and disease progression, and here we performed case reports of two of them.
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spelling doaj.art-a04b50db524042b9b19bd5b5166ef92d2023-07-21T19:00:00ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-07-011310.3389/fonc.2023.12079911207991Case Report: Exploration of changes in serum immunoinflammation-related protein complexes of patients with metastatic breast cancerChang Chen0Yali Xu1Zhizhen Lai2Zhili Li3Qiang Sun4Department of Breast Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Breast Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Biophysics and Structural Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, Beijing, ChinaDepartment of Biophysics and Structural Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, Beijing, ChinaDepartment of Breast Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaPatients with advanced breast cancer are difficult to treat and have poor prognosis. At present, the commonly used methods to monitor the disease progression of breast cancer are imaging examinations such as breast ultrasound, mammography and peripheral blood tumor markers such as carcinoembryonic antigen (CEA) and carbohydrate antigen 15-3 (CA15-3). However, none of them can detect tumor progression at an early stage. Serum immunoinflammation-related protein complexes (IIRPCs) showed potential to indicate cancer progression. Therefore, we attempted to monitor the level of IIRPCs in peripheral blood of patients with metastatic breast cancer and compare it with patients’ treatment and disease progression, and here we performed case reports of two of them.https://www.frontiersin.org/articles/10.3389/fonc.2023.1207991/fullimmunoinflammation-related protein complexesbreast cancerserumbiomarkerdisease surveillance
spellingShingle Chang Chen
Yali Xu
Zhizhen Lai
Zhili Li
Qiang Sun
Case Report: Exploration of changes in serum immunoinflammation-related protein complexes of patients with metastatic breast cancer
Frontiers in Oncology
immunoinflammation-related protein complexes
breast cancer
serum
biomarker
disease surveillance
title Case Report: Exploration of changes in serum immunoinflammation-related protein complexes of patients with metastatic breast cancer
title_full Case Report: Exploration of changes in serum immunoinflammation-related protein complexes of patients with metastatic breast cancer
title_fullStr Case Report: Exploration of changes in serum immunoinflammation-related protein complexes of patients with metastatic breast cancer
title_full_unstemmed Case Report: Exploration of changes in serum immunoinflammation-related protein complexes of patients with metastatic breast cancer
title_short Case Report: Exploration of changes in serum immunoinflammation-related protein complexes of patients with metastatic breast cancer
title_sort case report exploration of changes in serum immunoinflammation related protein complexes of patients with metastatic breast cancer
topic immunoinflammation-related protein complexes
breast cancer
serum
biomarker
disease surveillance
url https://www.frontiersin.org/articles/10.3389/fonc.2023.1207991/full
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