ANALYSIS OF INITIAL CLINICAL FEATURES OF PRIMARY IMMUNODEFICIENCIES IN ADULTS

At present, we are observing eighty-three adult patients with various primary immunodeficiencies (PID) of different origin. The aim of our study was to identify the optimal ways for early detection of such disorders. In this work, we present an analysis of initial clinical manifestations of PID in a...

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Main Authors: I. A. Tuzankina, M. L. Karakina, E. V. Vlasova
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2014-08-01
Series:Медицинская иммунология
Subjects:
Online Access:https://www.mimmun.ru/mimmun/article/view/703
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author I. A. Tuzankina
M. L. Karakina
E. V. Vlasova
author_facet I. A. Tuzankina
M. L. Karakina
E. V. Vlasova
author_sort I. A. Tuzankina
collection DOAJ
description At present, we are observing eighty-three adult patients with various primary immunodeficiencies (PID) of different origin. The aim of our study was to identify the optimal ways for early detection of such disorders. In this work, we present an analysis of initial clinical manifestations of PID in adults. It was revealed that the type of clinical manifestations is quite unique for individual cases. And the patients exhibit quite diverse clinical findings and course of the disorder, even within a single nosological entity. However, infectious syndrome prevailed among others manifestations. Combinations of complex clinical syndromes were not typical to initial PID pattern. We observed polytopic lesions within each single immunopathological syndrome.
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spelling doaj.art-a04eb4c37298460db3e1f5c2727b16042025-03-11T17:59:05ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-08-0116436737410.15789/1563-0625-2014-4-367-374700ANALYSIS OF INITIAL CLINICAL FEATURES OF PRIMARY IMMUNODEFICIENCIES IN ADULTSI. A. Tuzankina0M. L. Karakina1E. V. Vlasova2Institute of Clinical Immunology and Physiology, Ural Branch, Russian Academy of Sciences, Ekaterinburg Regional Children Clinical Hospital № 1, EkaterinburgInstitute of Clinical Immunology and Physiology, Ural Branch, Russian Academy of Sciences, Ekaterinburg Regional Children Clinical Hospital № 1, Ekaterinburg Regional Clinical Hospital № 1, EkaterinburgRegional Children Clinical Hospital № 1, EkaterinburgAt present, we are observing eighty-three adult patients with various primary immunodeficiencies (PID) of different origin. The aim of our study was to identify the optimal ways for early detection of such disorders. In this work, we present an analysis of initial clinical manifestations of PID in adults. It was revealed that the type of clinical manifestations is quite unique for individual cases. And the patients exhibit quite diverse clinical findings and course of the disorder, even within a single nosological entity. However, infectious syndrome prevailed among others manifestations. Combinations of complex clinical syndromes were not typical to initial PID pattern. We observed polytopic lesions within each single immunopathological syndrome.https://www.mimmun.ru/mimmun/article/view/703primary immunodeficienciesonsetclinical featuresearly detectionadults
spellingShingle I. A. Tuzankina
M. L. Karakina
E. V. Vlasova
ANALYSIS OF INITIAL CLINICAL FEATURES OF PRIMARY IMMUNODEFICIENCIES IN ADULTS
Медицинская иммунология
primary immunodeficiencies
onset
clinical features
early detection
adults
title ANALYSIS OF INITIAL CLINICAL FEATURES OF PRIMARY IMMUNODEFICIENCIES IN ADULTS
title_full ANALYSIS OF INITIAL CLINICAL FEATURES OF PRIMARY IMMUNODEFICIENCIES IN ADULTS
title_fullStr ANALYSIS OF INITIAL CLINICAL FEATURES OF PRIMARY IMMUNODEFICIENCIES IN ADULTS
title_full_unstemmed ANALYSIS OF INITIAL CLINICAL FEATURES OF PRIMARY IMMUNODEFICIENCIES IN ADULTS
title_short ANALYSIS OF INITIAL CLINICAL FEATURES OF PRIMARY IMMUNODEFICIENCIES IN ADULTS
title_sort analysis of initial clinical features of primary immunodeficiencies in adults
topic primary immunodeficiencies
onset
clinical features
early detection
adults
url https://www.mimmun.ru/mimmun/article/view/703
work_keys_str_mv AT iatuzankina analysisofinitialclinicalfeaturesofprimaryimmunodeficienciesinadults
AT mlkarakina analysisofinitialclinicalfeaturesofprimaryimmunodeficienciesinadults
AT evvlasova analysisofinitialclinicalfeaturesofprimaryimmunodeficienciesinadults