ANALYSIS OF INITIAL CLINICAL FEATURES OF PRIMARY IMMUNODEFICIENCIES IN ADULTS
At present, we are observing eighty-three adult patients with various primary immunodeficiencies (PID) of different origin. The aim of our study was to identify the optimal ways for early detection of such disorders. In this work, we present an analysis of initial clinical manifestations of PID in a...
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Format: | Article |
Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-08-01
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Series: | Медицинская иммунология |
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Online Access: | https://www.mimmun.ru/mimmun/article/view/703 |
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author | I. A. Tuzankina M. L. Karakina E. V. Vlasova |
author_facet | I. A. Tuzankina M. L. Karakina E. V. Vlasova |
author_sort | I. A. Tuzankina |
collection | DOAJ |
description | At present, we are observing eighty-three adult patients with various primary immunodeficiencies (PID) of different origin. The aim of our study was to identify the optimal ways for early detection of such disorders. In this work, we present an analysis of initial clinical manifestations of PID in adults. It was revealed that the type of clinical manifestations is quite unique for individual cases. And the patients exhibit quite diverse clinical findings and course of the disorder, even within a single nosological entity. However, infectious syndrome prevailed among others manifestations. Combinations of complex clinical syndromes were not typical to initial PID pattern. We observed polytopic lesions within each single immunopathological syndrome. |
first_indexed | 2024-03-08T05:49:58Z |
format | Article |
id | doaj.art-a04eb4c37298460db3e1f5c2727b1604 |
institution | Directory Open Access Journal |
issn | 1563-0625 2313-741X |
language | Russian |
last_indexed | 2025-03-14T02:20:23Z |
publishDate | 2014-08-01 |
publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
record_format | Article |
series | Медицинская иммунология |
spelling | doaj.art-a04eb4c37298460db3e1f5c2727b16042025-03-11T17:59:05ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-08-0116436737410.15789/1563-0625-2014-4-367-374700ANALYSIS OF INITIAL CLINICAL FEATURES OF PRIMARY IMMUNODEFICIENCIES IN ADULTSI. A. Tuzankina0M. L. Karakina1E. V. Vlasova2Institute of Clinical Immunology and Physiology, Ural Branch, Russian Academy of Sciences, Ekaterinburg Regional Children Clinical Hospital № 1, EkaterinburgInstitute of Clinical Immunology and Physiology, Ural Branch, Russian Academy of Sciences, Ekaterinburg Regional Children Clinical Hospital № 1, Ekaterinburg Regional Clinical Hospital № 1, EkaterinburgRegional Children Clinical Hospital № 1, EkaterinburgAt present, we are observing eighty-three adult patients with various primary immunodeficiencies (PID) of different origin. The aim of our study was to identify the optimal ways for early detection of such disorders. In this work, we present an analysis of initial clinical manifestations of PID in adults. It was revealed that the type of clinical manifestations is quite unique for individual cases. And the patients exhibit quite diverse clinical findings and course of the disorder, even within a single nosological entity. However, infectious syndrome prevailed among others manifestations. Combinations of complex clinical syndromes were not typical to initial PID pattern. We observed polytopic lesions within each single immunopathological syndrome.https://www.mimmun.ru/mimmun/article/view/703primary immunodeficienciesonsetclinical featuresearly detectionadults |
spellingShingle | I. A. Tuzankina M. L. Karakina E. V. Vlasova ANALYSIS OF INITIAL CLINICAL FEATURES OF PRIMARY IMMUNODEFICIENCIES IN ADULTS Медицинская иммунология primary immunodeficiencies onset clinical features early detection adults |
title | ANALYSIS OF INITIAL CLINICAL FEATURES OF PRIMARY IMMUNODEFICIENCIES IN ADULTS |
title_full | ANALYSIS OF INITIAL CLINICAL FEATURES OF PRIMARY IMMUNODEFICIENCIES IN ADULTS |
title_fullStr | ANALYSIS OF INITIAL CLINICAL FEATURES OF PRIMARY IMMUNODEFICIENCIES IN ADULTS |
title_full_unstemmed | ANALYSIS OF INITIAL CLINICAL FEATURES OF PRIMARY IMMUNODEFICIENCIES IN ADULTS |
title_short | ANALYSIS OF INITIAL CLINICAL FEATURES OF PRIMARY IMMUNODEFICIENCIES IN ADULTS |
title_sort | analysis of initial clinical features of primary immunodeficiencies in adults |
topic | primary immunodeficiencies onset clinical features early detection adults |
url | https://www.mimmun.ru/mimmun/article/view/703 |
work_keys_str_mv | AT iatuzankina analysisofinitialclinicalfeaturesofprimaryimmunodeficienciesinadults AT mlkarakina analysisofinitialclinicalfeaturesofprimaryimmunodeficienciesinadults AT evvlasova analysisofinitialclinicalfeaturesofprimaryimmunodeficienciesinadults |