Case series of intravenous thrombolysis for acute ischemic stroke in confirmed COVID-19 patients: single-centre experience
Abstract Background Coronavirus disease 2019 (COVID-19) not only caused a large surge of respiratory infections, it also had a potential association with and increases the risk of stroke. The pandemic has certainly provided new challenges and opportunities in the management of acute ischemic stroke...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-01-01
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| Series: | The Egyptian Journal of Neurology, Psychiatry and Neurosurgery |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s41983-021-00434-w |
| _version_ | 1798026252219580416 |
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| author | Ahmad Sulaiman Alwahdy Ika Yulieta Margaretha Kenyo Sembodro Pramesti Nailaufar Hamro Viska Yuzella Fitriani Nasution Arfan Mappalilu |
| author_facet | Ahmad Sulaiman Alwahdy Ika Yulieta Margaretha Kenyo Sembodro Pramesti Nailaufar Hamro Viska Yuzella Fitriani Nasution Arfan Mappalilu |
| author_sort | Ahmad Sulaiman Alwahdy |
| collection | DOAJ |
| description | Abstract Background Coronavirus disease 2019 (COVID-19) not only caused a large surge of respiratory infections, it also had a potential association with and increases the risk of stroke. The pandemic has certainly provided new challenges and opportunities in the management of acute ischemic stroke (AIS); however, data regarding outcomes of intravenous tissue plasminogen activator (IV TPA) administration in stroke patients with COVID-19 remains limited. Case presentation Three AIS patients with confirmed COVID-19 treated using IV tPA. One case had excellent outcome, while the other cases showed unfavorable results. The risk–benefit ratio of IV TPA in COVID-19 remains unclear. Conclusion In this article, we discuss the possible explanation behind these different outcomes. Although IV tPA could not cure COVID-19, we suggest that its administration should not be delayed in AIS patients with COVID-19. |
| first_indexed | 2024-04-11T18:32:18Z |
| format | Article |
| id | doaj.art-a053674731474020a35e4428e50bb218 |
| institution | Directory Open Access Journal |
| issn | 1687-8329 |
| language | English |
| last_indexed | 2024-04-11T18:32:18Z |
| publishDate | 2022-01-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Neurology, Psychiatry and Neurosurgery |
| spelling | doaj.art-a053674731474020a35e4428e50bb2182022-12-22T04:09:24ZengSpringerOpenThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery1687-83292022-01-015811710.1186/s41983-021-00434-wCase series of intravenous thrombolysis for acute ischemic stroke in confirmed COVID-19 patients: single-centre experienceAhmad Sulaiman Alwahdy0Ika Yulieta Margaretha1Kenyo Sembodro Pramesti2Nailaufar Hamro3Viska Yuzella4Fitriani Nasution5Arfan Mappalilu6Department of Neurology, Fatmawati Central General HospitalDepartment of Neurology, Fatmawati Central General HospitalUniversity of UIN Syarif HidayatullahUniversity of UIN Syarif HidayatullahUniversity of UIN Syarif HidayatullahDepartment of Neurology, Fatmawati Central General HospitalDepartment of Neurology, Fatmawati Central General HospitalAbstract Background Coronavirus disease 2019 (COVID-19) not only caused a large surge of respiratory infections, it also had a potential association with and increases the risk of stroke. The pandemic has certainly provided new challenges and opportunities in the management of acute ischemic stroke (AIS); however, data regarding outcomes of intravenous tissue plasminogen activator (IV TPA) administration in stroke patients with COVID-19 remains limited. Case presentation Three AIS patients with confirmed COVID-19 treated using IV tPA. One case had excellent outcome, while the other cases showed unfavorable results. The risk–benefit ratio of IV TPA in COVID-19 remains unclear. Conclusion In this article, we discuss the possible explanation behind these different outcomes. Although IV tPA could not cure COVID-19, we suggest that its administration should not be delayed in AIS patients with COVID-19.https://doi.org/10.1186/s41983-021-00434-wIschemic strokeIntravenous thrombolysisRt-PACOVID-19Case series |
| spellingShingle | Ahmad Sulaiman Alwahdy Ika Yulieta Margaretha Kenyo Sembodro Pramesti Nailaufar Hamro Viska Yuzella Fitriani Nasution Arfan Mappalilu Case series of intravenous thrombolysis for acute ischemic stroke in confirmed COVID-19 patients: single-centre experience The Egyptian Journal of Neurology, Psychiatry and Neurosurgery Ischemic stroke Intravenous thrombolysis Rt-PA COVID-19 Case series |
| title | Case series of intravenous thrombolysis for acute ischemic stroke in confirmed COVID-19 patients: single-centre experience |
| title_full | Case series of intravenous thrombolysis for acute ischemic stroke in confirmed COVID-19 patients: single-centre experience |
| title_fullStr | Case series of intravenous thrombolysis for acute ischemic stroke in confirmed COVID-19 patients: single-centre experience |
| title_full_unstemmed | Case series of intravenous thrombolysis for acute ischemic stroke in confirmed COVID-19 patients: single-centre experience |
| title_short | Case series of intravenous thrombolysis for acute ischemic stroke in confirmed COVID-19 patients: single-centre experience |
| title_sort | case series of intravenous thrombolysis for acute ischemic stroke in confirmed covid 19 patients single centre experience |
| topic | Ischemic stroke Intravenous thrombolysis Rt-PA COVID-19 Case series |
| url | https://doi.org/10.1186/s41983-021-00434-w |
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