Gene-encoding DNA origami for mammalian cell expression
DNA origami may enable more versatile gene delivery applications through its ability to create custom nanoscale objects. Here the authors show that genes folded in DNA origami with custom scaffolds express efficiently when delivered to mammalian cells and can be assembled into multimeric arrays to d...
Main Authors: | Jessica A. Kretzmann, Anna Liedl, Alba Monferrer, Volodymyr Mykhailiuk, Samuel Beerkens, Hendrik Dietz |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-02-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-36601-1 |
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