Optimisation of 2D U-Net Model Components for Automatic Prostate Segmentation on MRI

In this paper, we develop an optimised state-of-the-art 2D U-Net model by studying the effects of the individual deep learning model components in performing prostate segmentation. We found that for upsampling, the combination of interpolation and convolution is better than the use of transposed con...

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Main Authors: Indriani P. Astono, James S. Welsh, Stephan Chalup, Peter Greer
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/10/7/2601
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author Indriani P. Astono
James S. Welsh
Stephan Chalup
Peter Greer
author_facet Indriani P. Astono
James S. Welsh
Stephan Chalup
Peter Greer
author_sort Indriani P. Astono
collection DOAJ
description In this paper, we develop an optimised state-of-the-art 2D U-Net model by studying the effects of the individual deep learning model components in performing prostate segmentation. We found that for upsampling, the combination of interpolation and convolution is better than the use of transposed convolution. For combining feature maps in each convolution block, it is only beneficial if a skip connection with concatenation is used. With respect to pooling, average pooling is better than strided-convolution, max, RMS or L2 pooling. Introducing a batch normalisation layer before the activation layer gives further performance improvement. The optimisation is based on a private dataset as it has a fixed 2D resolution and voxel size for every image which mitigates the need of a resizing operation in the data preparation process. Non-enhancing data preprocessing was applied and five-fold cross-validation was used to evaluate the fully automatic segmentation approach. We show it outperforms the traditional methods that were previously applied on the private dataset, as well as outperforming other comparable state-of-the-art 2D models on the public dataset PROMISE12.
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spelling doaj.art-a0560b7d686541fb82465d24bb747fed2023-11-19T21:10:42ZengMDPI AGApplied Sciences2076-34172020-04-01107260110.3390/app10072601Optimisation of 2D U-Net Model Components for Automatic Prostate Segmentation on MRIIndriani P. Astono0James S. Welsh1Stephan Chalup2Peter Greer3School of Electrical Engineering and Computing, The University of Newcastle, Callaghan, NSW 2308, AustraliaSchool of Electrical Engineering and Computing, The University of Newcastle, Callaghan, NSW 2308, AustraliaSchool of Electrical Engineering and Computing, The University of Newcastle, Callaghan, NSW 2308, AustraliaSchool of Mathematical and Physical Sciences, The University of Newcastle, Callaghan, NSW 2308, AustraliaIn this paper, we develop an optimised state-of-the-art 2D U-Net model by studying the effects of the individual deep learning model components in performing prostate segmentation. We found that for upsampling, the combination of interpolation and convolution is better than the use of transposed convolution. For combining feature maps in each convolution block, it is only beneficial if a skip connection with concatenation is used. With respect to pooling, average pooling is better than strided-convolution, max, RMS or L2 pooling. Introducing a batch normalisation layer before the activation layer gives further performance improvement. The optimisation is based on a private dataset as it has a fixed 2D resolution and voxel size for every image which mitigates the need of a resizing operation in the data preparation process. Non-enhancing data preprocessing was applied and five-fold cross-validation was used to evaluate the fully automatic segmentation approach. We show it outperforms the traditional methods that were previously applied on the private dataset, as well as outperforming other comparable state-of-the-art 2D models on the public dataset PROMISE12.https://www.mdpi.com/2076-3417/10/7/2601convolutional neural networksmedical image applicationprostate segmentationmagnetic resonance imagingMRI
spellingShingle Indriani P. Astono
James S. Welsh
Stephan Chalup
Peter Greer
Optimisation of 2D U-Net Model Components for Automatic Prostate Segmentation on MRI
Applied Sciences
convolutional neural networks
medical image application
prostate segmentation
magnetic resonance imaging
MRI
title Optimisation of 2D U-Net Model Components for Automatic Prostate Segmentation on MRI
title_full Optimisation of 2D U-Net Model Components for Automatic Prostate Segmentation on MRI
title_fullStr Optimisation of 2D U-Net Model Components for Automatic Prostate Segmentation on MRI
title_full_unstemmed Optimisation of 2D U-Net Model Components for Automatic Prostate Segmentation on MRI
title_short Optimisation of 2D U-Net Model Components for Automatic Prostate Segmentation on MRI
title_sort optimisation of 2d u net model components for automatic prostate segmentation on mri
topic convolutional neural networks
medical image application
prostate segmentation
magnetic resonance imaging
MRI
url https://www.mdpi.com/2076-3417/10/7/2601
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