Methylation Patterns of the FKBP5 Gene in Association with Childhood Maltreatment and Depressive Disorders

Methylation Patterns of the FKBP5 Gene in Association with Childhood Maltreatment and Depressive Disorders

Childhood maltreatment is an important risk factor for adult depression and has been associated with changes in the hypothalamic pituitary adrenal (HPA) axis, including cortisol secretion and methylation of the <i>FKBP5</i> gene. Furthermore, associations between depression and HPA chang...

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Bibliographic Details
Main Authors: Nora L. Großmann, Antoine Weihs, Luise Kühn, Susann Sauer, Simone Röh, Tobias Wiechmann, Monika Rex-Haffner, Henry Völzke, Uwe Völker, Elisabeth B. Binder, Alexander Teumer, Georg Homuth, Johanna Klinger-König, Hans J. Grabe
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
childhood maltreatment
depression
HPA
epigenetics
stress
cortisol
Online Access:https://www.mdpi.com/1422-0067/25/3/1485

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