Pyrrolylquinoxaline-2-One Derivative as a Potent Therapeutic Factor for Brain Trauma Rehabilitation

Pyrrolylquinoxaline-2-One Derivative as a Potent Therapeutic Factor for Brain Trauma Rehabilitation

Traumatic brain injury (TBI) often causes massive brain cell death accompanied by the accumulation of toxic factors in interstitial and cerebrospinal fluids. The persistence of the damaged brain area is not transient and may occur within days and weeks. Chaperone Hsp70 is known for its cytoprotectiv...

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Bibliographic Details
Main Authors: Elizaveta A. Dutysheva, Marina A. Mikeladze, Maria A. Trestsova, Nikolay D. Aksenov, Irina A. Utepova, Elena R. Mikhaylova, Roman V. Suezov, Valery N. Charushin, Oleg N. Chupakhin, Irina V. Guzhova, Boris A. Margulis, Vladimir F. Lazarev
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pharmaceutics
Subjects:
traumatic brain injury
cerebrospinal fluid
Hsp70
small molecule
apoptosis
Online Access:https://www.mdpi.com/1999-4923/12/5/414

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https://www.mdpi.com/1999-4923/12/5/414

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