Interleukin-22 signaling attenuates necrotizing enterocolitis by promoting epithelial cell regeneration

Interleukin-22 signaling attenuates necrotizing enterocolitis by promoting epithelial cell regeneration

Summary: Necrotizing enterocolitis (NEC) is a deadly intestinal inflammatory disorder that primarily affects premature infants and lacks adequate therapeutics. Interleukin (IL)-22 plays a critical role in gut barrier maintenance, promoting epithelial regeneration, and controlling intestinal inflamma...

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Bibliographic Details
Main Authors: Belgacem Mihi, Qingqing Gong, Lila S. Nolan, Sarah E. Gale, Martin Goree, Elise Hu, Wyatt E. Lanik, Jamie M. Rimer, Victoria Liu, Olivia B. Parks, Angela N. Lewis, Pranjal Agrawal, Marie L. Laury, Pawan Kumar, Elizabeth Huang, Shay S. Bidani, Cliff J. Luke, Jay K. Kolls, Misty Good
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Cell Reports Medicine
Subjects:
interleukin-22
necrotizing enterocolitis
epithelial cells
microbiome
regeneration
intestinal immunity
Online Access:http://www.sciencedirect.com/science/article/pii/S2666379121001634

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