Pretreatment blood biomarkers combined with magnetic resonance imaging predict responses to neoadjuvant chemoradiotherapy in locally advanced rectal cancer

Pretreatment blood biomarkers combined with magnetic resonance imaging predict responses to neoadjuvant chemoradiotherapy in locally advanced rectal cancer

AimTo investigate the value of pretreatment blood biomarkers combined with magnetic resonance imaging (MRI) in predicting the efficacy of neoadjuvant chemoradiotherapy (NCRT) in patients with locally advanced rectal cancer (LARC).MethodsThis study involved patients with LARC who received NCRT and su...

Full description

Bibliographic Details
Main Authors:	Xinyu Shi, Min Zhao, Bo Shi, Guoliang Chen, Huihui Yao, Junjie Chen, Daiwei Wan, Wen Gu, Songbing He
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-08-01
Series:	Frontiers in Oncology
Subjects:	locally advanced rectal cancer neoadjuvant chemoradiotherapy pathological complete response blood biomarkers magnetic resonance imaging prognosis
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2022.916840/full

Similar Items

results of neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer. Comparative efficiency of hypofractionation and classical fractionation schedules
by: A. S. Abdujapparov, et al.
Published: (2020-08-01)

Prediction of Survival Status of Locally Advanced Rectal Cancer after Neoadjuvant Chemoradiotherapy Based on Improved Fully Convolutional Networks Model
by: WANG Fang, et al.
Published: (2022-07-01)

Surgery may not benefit patients with locally advanced rectal cancer who achieved clinical complete response following neoadjuvant chemoradiotherapy
by: Zihan Han, et al.
Published: (2022-01-01)

2-CONSERVATIVE TREATMENT OF RECTAL ADENOCARCINOMA AFTER NEOADJUVANT CHEMORADIOTHERAPY, IS IT ACCEPTABLE?
by: Majeed H Alwan
Published: (2009-06-01)

Pretreatment Neutrophil-to-Lymphocyte Ratio Associated with Tumor Recurrence and Survival in Patients Achieving a Pathological Complete Response Following Neoadjuvant Chemoradiotherapy for Rectal Cancer
by: Chun-Ming Huang, et al.
Published: (2021-09-01)

Adding Three Cycles of CAPOX after Neoadjuvant Chemoradiotherapy Increases the Rates of Complete Response for Locally Advanced Rectal Cancer
by: Zhiwei Zhai, et al.
Published: (2021-01-01)

Predictors and Risk Factors of Pathologic Complete Response Following Neoadjuvant Chemoradiotherapy for Rectal Cancer: A Population-Based Analysis
by: Yinuo Tan, et al.
Published: (2019-06-01)

Meta-analysis of neoadjuvant chemotherapy versus neoadjuvant chemoradiotherapy for locally advanced rectal cancer
by: Huaqin Lin, et al.
Published: (2021-05-01)

The potential predictive value of DEK expression for neoadjuvant chemoradiotherapy response in locally advanced rectal cancer
by: J. Martinez-Useros, et al.
Published: (2018-02-01)

Deep Learning Model for Predicting the Pathological Complete Response to Neoadjuvant Chemoradiotherapy of Locally Advanced Rectal Cancer
by: Xiaoying Lou, et al.
Published: (2022-06-01)

Accuracy of high-resolution rectal magnetic resonance imaging re-staging with histopathology in locally advanced rectal cancer after neoadjuvant chemoradiotherapy
by: Supparerk Laohawiriyakamol, et al.
Published: (2021-01-01)

Short-Term Clinical and Oncological Outcome of Prolonging Operation Interval After Neoadjuvant Chemoradiotherapy for Locally Advanced Middle and Low Rectal Cancer
by: Yang J, et al.
Published: (2020-03-01)

Surgical treatment following neoadjuvant chemoradiotherapy in locally advanced rectal cancer
by: Ming‐Yii Huang, et al.
Published: (2020-03-01)

Neoadjuvant chemoradiotherapy in combined treatment of patients with rectal cancer
by: N. A. Maistrenko, et al.
Published: (2017-08-01)

Tumor-Infiltrating Cytotoxic T Cells and Tumor-Associated Macrophages Correlate With the Outcomes of Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer
by: Yuqin Yang, et al.
Published: (2021-10-01)

Associations between clinical characteristics and tumor response to neoadjuvant chemoradiotherapy in rectal cancer
by: Xiaolin Pang, et al.
Published: (2021-07-01)

A multiple-time-scale comparative study for the added value of magnetic resonance imaging-based radiomics in predicting pathological complete response after neoadjuvant chemoradiotherapy in locally advanced rectal cancer
by: Wenjing Peng, et al.
Published: (2023-08-01)

Predictive and Prognostic Value of Oncogene Mutations and Microsatellite Instability in Locally-Advanced Rectal Cancer Treated with Neoadjuvant Radiation-Based Therapy: A Systematic Review and Meta-Analysis
by: Elena De Mattia, et al.
Published: (2023-02-01)

Performance and Dimensionality of Pretreatment MRI Radiomics in Rectal Carcinoma Chemoradiotherapy Prediction
by: Mladen Marinkovic, et al.
Published: (2024-01-01)

Total neoadjuvant therapy with short-course radiotherapy Versus long-course neoadjuvant chemoradiotherapy in Locally Advanced Rectal cancer, Korean trial (TV-LARK trial): study protocol of a multicentre randomized controlled trial
by: Min Jung Kim, et al.
Published: (2023-08-01)

Body composition parameters combined with blood biomarkers and magnetic resonance imaging predict responses to neoadjuvant chemoradiotherapy in locally advanced rectal cancer
by: Jianguo Yang, et al.
Published: (2023-11-01)

Influencing factors and establishment of a prediction model for the tumor regression after neoadjuvant chemoradiotherapy in locally advanced rectal cancer
by: LIU Zhiyu, XU Dong, CHEN Xihao, LI Jipeng
Published: (2024-02-01)

A Nomogram for Predicting Pathological Complete Response to Neoadjuvant Chemoradiotherapy Using Semiquantitative Parameters Derived From Sequential PET/CT in Locally Advanced Rectal Cancer
by: Dae Hee Pyo, et al.
Published: (2021-10-01)

A Case with Rectal Cancer Relapses After Clinical Complete Remission Following Neoadjuvant Chemoradiotherapy
by: Zhang PB, et al.
Published: (2019-12-01)

Diagnostic performance of magnetic resonance imaging in preoperative local staging of rectal cancer after neoadjuvant chemoradiotherapy
by: Hakkı Çelik, et al.
Published: (2023-03-01)

Radiomics Signature Based on Support Vector Machines for the Prediction of Pathological Complete Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer
by: Chao Li, et al.
Published: (2023-10-01)

Prognostic value of mesorectal package area in patients with locally advanced rectal cancer following neoadjuvant chemoradiotherapy: A retrospective cohort study
by: Bingjie Guan, et al.
Published: (2022-10-01)

Predicting rectal tumor response to neoadjuvant chemoradiotherapy using plasma levels of carcinoembryonic antigen (CEA): Results from a tertiary center in Iran
by: Hadi Ahmadi Amoli, MD, et al.
Published: (2022-12-01)

Efficacy of modified neoadjuvant chemoradiotherapy in locally advanced rectal cancer: A single institution experience in Taiwan
by: Yi-Ying Wu, et al.
Published: (2014-01-01)

Impact of glucocorticoids on the efficacy of neoadjuvant chemoradiotherapy and survival of patients with locally advanced rectal cancer: a retrospective study
by: Xiaoxue Huang, et al.
Published: (2023-03-01)

Clinical benefits of oral capecitabine over intravenous 5-fluorouracyl regimen in case of neoadjuvant chemoradiotherapy followed by surgery for locally advanced rectal cancer
by: Attila Paszt, et al.
Published: (2022-12-01)

Poor prognostic and staging value of tumor deposit in locally advanced rectal cancer with neoadjuvant chemoradiotherapy
by: Yaqi Wang, et al.
Published: (2019-04-01)

Induction chemotherapy, chemoradiotherapy and consolidation chemotherapy in preoperative treatment of rectal cancer - long-term results of phase II OIGIT-01 Trial
by: Golo Danijela, et al.
Published: (2018-09-01)

Identification of proteomic markers for prediction of the response to 5-Fluorouracil based neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients
by: Jianan Wang, et al.
Published: (2022-03-01)

A novel LARCassigner3 classification predicts outcomes in patients with locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy: a retrospective training and validation analysis
by: Zhang J, et al.
Published: (2019-05-01)

Analysis of Survival in Complete Pathological Response after Long-Course Chemoradiotherapy in Patients with Advanced Rectal Cancer
by: Cemal Ulusoy, et al.
Published: (2023-01-01)

The reduction of 18F-FDG uptake ability of tumor tissue after neoadjuvant chemoradiotherapy in locally advanced rectal cancer can effectively reflect the degree of tumor regression
by: Fengpeng Wu, et al.
Published: (2022-12-01)

Nomogram Predicting Overall Survival of Resected Locally Advanced Rectal Cancer Patients with Neoadjuvant Chemoradiotherapy
by: Song J, et al.
Published: (2020-08-01)

Clinical benefit of adding oxaliplatin to standard neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a meta-analysis
by: Francesca De Felice, et al.
Published: (2017-05-01)

Oncologic Outcomes in Patients Who Undergo Neoadjuvant Chemoradiotherapy and Total Mesorectal Excision for Locally Advanced Rectal Cancer: A 14-Year Experience in a Single Institution
by: Min Jung Kim, et al.
Published: (2019-04-01)