Characteristics associated with quality of life in the early stages of Mycosis Fungoides
Background: Mycosis fungoides (MF) is a lymphoproliferative disorder characterized by skin-homing atypical lymphocytes. This study aimed to evaluate the quality of life (QoL) in MF patients in the early stages of the disease and the associated factors using the Dermatology Life Quality Index (DLQI)....
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| Format: | Article |
| Language: | English |
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Babol University of Medical Sciences
2023-01-01
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| Series: | Caspian Journal of Internal Medicine |
| Subjects: | |
| Online Access: | http://caspjim.com/article-1-3025-en.html |
| _version_ | 1797957176605540352 |
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| author | Pedram Nourmohammadpour Maryam Nasimi Zeinab Aryanian Azadeh Goodarzi Reyhaneh Jahazi Ifa Etesami |
| author_facet | Pedram Nourmohammadpour Maryam Nasimi Zeinab Aryanian Azadeh Goodarzi Reyhaneh Jahazi Ifa Etesami |
| author_sort | Pedram Nourmohammadpour |
| collection | DOAJ |
| description | Background: Mycosis fungoides (MF) is a lymphoproliferative disorder characterized by skin-homing atypical lymphocytes. This study aimed to evaluate the quality of life (QoL) in MF patients in the early stages of the disease and the associated factors using the Dermatology Life Quality Index (DLQI).
Methods: Thirty MF patients (21 females/9 males) with a mean age of 46.73±15.9 years and in the early stages of the disease (26 stage Ι and 4 stage ΙΙ) were enrolled and were asked to fill the DLQI questionnaire.
Results: The mean DLQI score was 9.93±5.89. The QoL was largely affected by the disease in near half of the patients (46.7% of patients had a DLQI score11-20). QoL was significantly correlated with educational level and was more impaired in patients with lower educational status (DLQI score spearman rho=-0.382, P=0.037). QoL was not associated with sex, age, disease stage and disease duration. The symptom and feeling dimension of DLQI was significantly more impaired in patients with both patch and plaque compared to patch only (spearman rho= 0.397, P= 0.03).
Conclusion: This study demonstrates how largely patients’ QoL is influenced in the early stages of MF, especially in patients with lower educational levels. |
| first_indexed | 2024-04-11T00:00:16Z |
| format | Article |
| id | doaj.art-a0640ac25e4c426e9c9f0073767efb73 |
| institution | Directory Open Access Journal |
| issn | 2008-6164 2008-6172 |
| language | English |
| last_indexed | 2024-04-11T00:00:16Z |
| publishDate | 2023-01-01 |
| publisher | Babol University of Medical Sciences |
| record_format | Article |
| series | Caspian Journal of Internal Medicine |
| spelling | doaj.art-a0640ac25e4c426e9c9f0073767efb732023-01-10T05:28:09ZengBabol University of Medical SciencesCaspian Journal of Internal Medicine2008-61642008-61722023-01-011411622Characteristics associated with quality of life in the early stages of Mycosis FungoidesPedram Nourmohammadpour0Maryam Nasimi1Zeinab Aryanian2Azadeh Goodarzi3Reyhaneh Jahazi4Ifa Etesami5 Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, b Department of Dermatology, Babol University of Medical Sciences, Babol, Iran Department of Dermatology, Rasool Akram Medical Complex, Iran University of Medical Sciences (IUMS), Tehran, Iran Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran b. Autoimmune Bullous Diseases Research Center, Dermatology Department, Tehran University of Medical Sciences, Tehran, Iran Background: Mycosis fungoides (MF) is a lymphoproliferative disorder characterized by skin-homing atypical lymphocytes. This study aimed to evaluate the quality of life (QoL) in MF patients in the early stages of the disease and the associated factors using the Dermatology Life Quality Index (DLQI). Methods: Thirty MF patients (21 females/9 males) with a mean age of 46.73±15.9 years and in the early stages of the disease (26 stage Ι and 4 stage ΙΙ) were enrolled and were asked to fill the DLQI questionnaire. Results: The mean DLQI score was 9.93±5.89. The QoL was largely affected by the disease in near half of the patients (46.7% of patients had a DLQI score11-20). QoL was significantly correlated with educational level and was more impaired in patients with lower educational status (DLQI score spearman rho=-0.382, P=0.037). QoL was not associated with sex, age, disease stage and disease duration. The symptom and feeling dimension of DLQI was significantly more impaired in patients with both patch and plaque compared to patch only (spearman rho= 0.397, P= 0.03). Conclusion: This study demonstrates how largely patients’ QoL is influenced in the early stages of MF, especially in patients with lower educational levels.http://caspjim.com/article-1-3025-en.htmlmycosis fungoidesquality of lifelymphoproliferative disorders |
| spellingShingle | Pedram Nourmohammadpour Maryam Nasimi Zeinab Aryanian Azadeh Goodarzi Reyhaneh Jahazi Ifa Etesami Characteristics associated with quality of life in the early stages of Mycosis Fungoides Caspian Journal of Internal Medicine mycosis fungoides quality of life lymphoproliferative disorders |
| title | Characteristics associated with quality of life in the early stages of Mycosis Fungoides |
| title_full | Characteristics associated with quality of life in the early stages of Mycosis Fungoides |
| title_fullStr | Characteristics associated with quality of life in the early stages of Mycosis Fungoides |
| title_full_unstemmed | Characteristics associated with quality of life in the early stages of Mycosis Fungoides |
| title_short | Characteristics associated with quality of life in the early stages of Mycosis Fungoides |
| title_sort | characteristics associated with quality of life in the early stages of mycosis fungoides |
| topic | mycosis fungoides quality of life lymphoproliferative disorders |
| url | http://caspjim.com/article-1-3025-en.html |
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