Modulation of Antigen Display on PapMV Nanoparticles Influences Its Immunogenicity

Modulation of Antigen Display on PapMV Nanoparticles Influences Its Immunogenicity

Background: The papaya mosaic virus (PapMV) vaccine platform is a rod-shaped nanoparticle made of the recombinant PapMV coat protein (CP) self-assembled around a noncoding single-stranded RNA (ssRNA) template. The PapMV nanoparticle induces innate immunity through stimulation of the Toll-like recept...

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Bibliographic Details
Main Authors: Marie-Eve Laliberté-Gagné, Marilène Bolduc, Caroline Garneau, Santa-Mariela Olivera-Ugarte, Pierre Savard, Denis Leclerc
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Vaccines
Subjects:
vaccine platform
papaya mosaic virus (PapMV)
rod-shaped nanoparticle
influenza M2e
influenza nucleocapsid
sortase (SrtA)
Online Access:https://www.mdpi.com/2076-393X/9/1/33

Internet

https://www.mdpi.com/2076-393X/9/1/33

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