Reference compounds for characterizing cellular injury in high-content cellular morphology assays
Cellular nuisance compounds are a burden in chemical biology and drug screening. Here the authors profile prototypical cytotoxic and nuisance compounds using the cell painting assay to systematically characterise cellular morphologies associated with compound-dependent cellular injury and nuisance a...
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Bibliographic Details
| Main Authors: |
Jayme L. Dahlin,
Bruce K. Hua,
Beth E. Zucconi,
Shawn D. Nelson,
Shantanu Singh,
Anne E. Carpenter,
Jonathan H. Shrimp,
Evelyne Lima-Fernandes,
Mathias J. Wawer,
Lawrence P. W. Chung,
Ayushi Agrawal,
Mary O’Reilly,
Dalia Barsyte-Lovejoy,
Magdalena Szewczyk,
Fengling Li,
Parnian Lak,
Matthew Cuellar,
Philip A. Cole,
Jordan L. Meier,
Tim Thomas,
Jonathan B. Baell,
Peter J. Brown,
Michael A. Walters,
Paul A. Clemons,
Stuart L. Schreiber,
Bridget K. Wagner |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2023-03-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-023-36829-x
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