HEALTH-RELATED QUALITY OF LIFE ASSESSMENT IN PATIENTS WITH RECTAL CANCER TREATED WITH CURATIVE INTENT
ABSTRACT BACKGROUND: The treatment of median and distal rectal cancer has evolved a lot in the last decades due to the dissemination of the technique of total mesortal excision and the use of neoadjuvant chemotherapy and radiotherapy. However, this multidisciplinary approach can affect patients’ q...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE)
|
| Series: | Arquivos de Gastroenterologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032018000200154&lng=en&tlng=en |
| _version_ | 1818043712674988032 |
|---|---|
| author | José Luís da Costa Alves de SOUZA Caio Sergio Rizkallah NAHAS Sergio Carlos NAHAS Carlos Frederico Sparapan MARQUES Ulysses RIBEIRO JÚNIOR Ivan CECCONELLO |
| author_facet | José Luís da Costa Alves de SOUZA Caio Sergio Rizkallah NAHAS Sergio Carlos NAHAS Carlos Frederico Sparapan MARQUES Ulysses RIBEIRO JÚNIOR Ivan CECCONELLO |
| author_sort | José Luís da Costa Alves de SOUZA |
| collection | DOAJ |
| description | ABSTRACT BACKGROUND: The treatment of median and distal rectal cancer has evolved a lot in the last decades due to the dissemination of the technique of total mesortal excision and the use of neoadjuvant chemotherapy and radiotherapy. However, this multidisciplinary approach can affect patients’ quality of life in a number of ways that deserve to be adequately assessed. OBJECTIVE: To evaluate immediate and late health related quality of life in patients with rectal cancer treated with curative intent. METHODS: Prospective study including patients with non-metastatic mid or low rectal cancer. EORTC QLQ-C30 and EORTC-CR38 questionnaires were applied before, 3 months and 12 months after treatment. The mean scores of the questionnaires were stratified into 4 categories for the purpose of comparing the results at different moments. RESULTS: Twenty nine patients completed the 1st and 2nd questionnaires and 12 completed the three questionaries. Patient´s mean age was 50.8 years and 62% were female. Sphincter preservation was possible in 89.6%. Overall health scores and quality of life improved after three months after 12 months. After three months, sexual satisfaction, female sexual problems and future perspective were worsen, but gastrointestinal symptoms, sphincter problems, and weight loss were improved. After 12 months the Future Perspective deteriorated, but there was improvement of the problems related to stoma, sphincter problems and body image. CONCLUSION: Despite the complexity of the treatment of rectal cancer within a specialized service, quality of life was preserved and was satisfactory in most of the studied aspects. |
| first_indexed | 2024-12-10T09:06:34Z |
| format | Article |
| id | doaj.art-a065cfd6c05540c5823dedd68cc47847 |
| institution | Directory Open Access Journal |
| issn | 1678-4219 |
| language | English |
| last_indexed | 2024-12-10T09:06:34Z |
| publisher | Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE) |
| record_format | Article |
| series | Arquivos de Gastroenterologia |
| spelling | doaj.art-a065cfd6c05540c5823dedd68cc478472022-12-22T01:55:08ZengInstituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE)Arquivos de Gastroenterologia1678-421955215415910.1590/s0004-2803.201800000-27S0004-28032018000200154HEALTH-RELATED QUALITY OF LIFE ASSESSMENT IN PATIENTS WITH RECTAL CANCER TREATED WITH CURATIVE INTENTJosé Luís da Costa Alves de SOUZACaio Sergio Rizkallah NAHASSergio Carlos NAHASCarlos Frederico Sparapan MARQUESUlysses RIBEIRO JÚNIORIvan CECCONELLOABSTRACT BACKGROUND: The treatment of median and distal rectal cancer has evolved a lot in the last decades due to the dissemination of the technique of total mesortal excision and the use of neoadjuvant chemotherapy and radiotherapy. However, this multidisciplinary approach can affect patients’ quality of life in a number of ways that deserve to be adequately assessed. OBJECTIVE: To evaluate immediate and late health related quality of life in patients with rectal cancer treated with curative intent. METHODS: Prospective study including patients with non-metastatic mid or low rectal cancer. EORTC QLQ-C30 and EORTC-CR38 questionnaires were applied before, 3 months and 12 months after treatment. The mean scores of the questionnaires were stratified into 4 categories for the purpose of comparing the results at different moments. RESULTS: Twenty nine patients completed the 1st and 2nd questionnaires and 12 completed the three questionaries. Patient´s mean age was 50.8 years and 62% were female. Sphincter preservation was possible in 89.6%. Overall health scores and quality of life improved after three months after 12 months. After three months, sexual satisfaction, female sexual problems and future perspective were worsen, but gastrointestinal symptoms, sphincter problems, and weight loss were improved. After 12 months the Future Perspective deteriorated, but there was improvement of the problems related to stoma, sphincter problems and body image. CONCLUSION: Despite the complexity of the treatment of rectal cancer within a specialized service, quality of life was preserved and was satisfactory in most of the studied aspects.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032018000200154&lng=en&tlng=enQuality of lifeRectal neoplasmsHealth related quality of lifeColorectal neoplasms |
| spellingShingle | José Luís da Costa Alves de SOUZA Caio Sergio Rizkallah NAHAS Sergio Carlos NAHAS Carlos Frederico Sparapan MARQUES Ulysses RIBEIRO JÚNIOR Ivan CECCONELLO HEALTH-RELATED QUALITY OF LIFE ASSESSMENT IN PATIENTS WITH RECTAL CANCER TREATED WITH CURATIVE INTENT Arquivos de Gastroenterologia Quality of life Rectal neoplasms Health related quality of life Colorectal neoplasms |
| title | HEALTH-RELATED QUALITY OF LIFE ASSESSMENT IN PATIENTS WITH RECTAL CANCER TREATED WITH CURATIVE INTENT |
| title_full | HEALTH-RELATED QUALITY OF LIFE ASSESSMENT IN PATIENTS WITH RECTAL CANCER TREATED WITH CURATIVE INTENT |
| title_fullStr | HEALTH-RELATED QUALITY OF LIFE ASSESSMENT IN PATIENTS WITH RECTAL CANCER TREATED WITH CURATIVE INTENT |
| title_full_unstemmed | HEALTH-RELATED QUALITY OF LIFE ASSESSMENT IN PATIENTS WITH RECTAL CANCER TREATED WITH CURATIVE INTENT |
| title_short | HEALTH-RELATED QUALITY OF LIFE ASSESSMENT IN PATIENTS WITH RECTAL CANCER TREATED WITH CURATIVE INTENT |
| title_sort | health related quality of life assessment in patients with rectal cancer treated with curative intent |
| topic | Quality of life Rectal neoplasms Health related quality of life Colorectal neoplasms |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032018000200154&lng=en&tlng=en |
| work_keys_str_mv | AT joseluisdacostaalvesdesouza healthrelatedqualityoflifeassessmentinpatientswithrectalcancertreatedwithcurativeintent AT caiosergiorizkallahnahas healthrelatedqualityoflifeassessmentinpatientswithrectalcancertreatedwithcurativeintent AT sergiocarlosnahas healthrelatedqualityoflifeassessmentinpatientswithrectalcancertreatedwithcurativeintent AT carlosfredericosparapanmarques healthrelatedqualityoflifeassessmentinpatientswithrectalcancertreatedwithcurativeintent AT ulyssesribeirojunior healthrelatedqualityoflifeassessmentinpatientswithrectalcancertreatedwithcurativeintent AT ivancecconello healthrelatedqualityoflifeassessmentinpatientswithrectalcancertreatedwithcurativeintent |