Distinct transcriptomic and epigenomic modalities underpin human memory T cell subsets and their activation potential
An integrated analysis uncovers transcriptional and epigenetic differences of human circulating memory T cell subsets and identifies unique transcription factor networks associated with memory subset differentiation.
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-04-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-023-04747-9 |
| _version_ | 1797849917074440192 |
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| author | James R. Rose Bagdeser Akdogan-Ozdilek Andrew R. Rahmberg Michael D. Powell Sakeenah L. Hicks Christopher D. Scharer Jeremy M. Boss |
| author_facet | James R. Rose Bagdeser Akdogan-Ozdilek Andrew R. Rahmberg Michael D. Powell Sakeenah L. Hicks Christopher D. Scharer Jeremy M. Boss |
| author_sort | James R. Rose |
| collection | DOAJ |
| description | An integrated analysis uncovers transcriptional and epigenetic differences of human circulating memory T cell subsets and identifies unique transcription factor networks associated with memory subset differentiation. |
| first_indexed | 2024-04-09T18:51:55Z |
| format | Article |
| id | doaj.art-a067bd43035a480cbc06a1f70910044e |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-09T18:51:55Z |
| publishDate | 2023-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-a067bd43035a480cbc06a1f70910044e2023-04-09T11:24:26ZengNature PortfolioCommunications Biology2399-36422023-04-016111910.1038/s42003-023-04747-9Distinct transcriptomic and epigenomic modalities underpin human memory T cell subsets and their activation potentialJames R. Rose0Bagdeser Akdogan-Ozdilek1Andrew R. Rahmberg2Michael D. Powell3Sakeenah L. Hicks4Christopher D. Scharer5Jeremy M. Boss6Department of Microbiology and Immunology, and the Emory Vaccine Center, Emory University School of MedicineDepartment of Microbiology and Immunology, and the Emory Vaccine Center, Emory University School of MedicineBarrier Immunity Section, Laboratory of Viral Diseases, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, NIHDepartment of Microbiology and Immunology, and the Emory Vaccine Center, Emory University School of MedicineDepartment of Microbiology and Immunology, and the Emory Vaccine Center, Emory University School of MedicineDepartment of Microbiology and Immunology, and the Emory Vaccine Center, Emory University School of MedicineDepartment of Microbiology and Immunology, and the Emory Vaccine Center, Emory University School of MedicineAn integrated analysis uncovers transcriptional and epigenetic differences of human circulating memory T cell subsets and identifies unique transcription factor networks associated with memory subset differentiation.https://doi.org/10.1038/s42003-023-04747-9 |
| spellingShingle | James R. Rose Bagdeser Akdogan-Ozdilek Andrew R. Rahmberg Michael D. Powell Sakeenah L. Hicks Christopher D. Scharer Jeremy M. Boss Distinct transcriptomic and epigenomic modalities underpin human memory T cell subsets and their activation potential Communications Biology |
| title | Distinct transcriptomic and epigenomic modalities underpin human memory T cell subsets and their activation potential |
| title_full | Distinct transcriptomic and epigenomic modalities underpin human memory T cell subsets and their activation potential |
| title_fullStr | Distinct transcriptomic and epigenomic modalities underpin human memory T cell subsets and their activation potential |
| title_full_unstemmed | Distinct transcriptomic and epigenomic modalities underpin human memory T cell subsets and their activation potential |
| title_short | Distinct transcriptomic and epigenomic modalities underpin human memory T cell subsets and their activation potential |
| title_sort | distinct transcriptomic and epigenomic modalities underpin human memory t cell subsets and their activation potential |
| url | https://doi.org/10.1038/s42003-023-04747-9 |
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