Esophageal squamous cell carcinoma with EP300 mutations displays distinct genetic characteristics relevant to neoadjuvant chemoradiotherapy

Esophageal squamous cell carcinoma with EP300 mutations displays distinct genetic characteristics relevant to neoadjuvant chemoradiotherapy

Abstract Background EP300 mutation is common in esophageal squamous cell carcinoma (ESCC). We aimed to analyze the influence of EP300 mutation on treatment effect and prognosis in ESCC patients underwent neoadjuvant chemoradiotherapy. Method Thirty ESCC patients treated with neoadjuvant chemoradioth...

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Manylion Llyfryddiaeth
Prif Awduron: Yutian Lai, Yingxian Dong, Long Tian, Hongjun Li, Xinyi Ye, Yang Hu
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: BMC 2025-01-01
Cyfres:World Journal of Surgical Oncology
Pynciau:
Esophageal squamous cell carcinoma
Neoadjuvant chemoradiotherapy
EP300
Immune activity
Tumor microenvironment
Mynediad Ar-lein:https://doi.org/10.1186/s12957-024-03642-9

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https://doi.org/10.1186/s12957-024-03642-9

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