Pregnancy Rates after Hysteroscopic Endometrial Polypectomy versus Endometrial Curettage Polypectomy: A Retrospective Study
<i>Background and Objectives</i>: A relationship between endometrial polypectomy and in vitro fertilization (IVF) pregnancy outcomes has been reported; however, only a few studies have compared polyp removal techniques and pregnancy rates. We investigated whether different polypectomy te...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
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MDPI AG
2023-10-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/59/10/1868 |
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| author | Mikiko Nishioka Tadashi Maezawa Hiroki Takeuchi Katsuyuki Hagiwara Sachiyo Tarui Mito Sakamoto Erina Takayama Hideaki Yajima Eiji Kondo Hiroaki Kawato Hiroyuki Minoura Ken Sugaya Aisaku Fukuda Tomoaki Ikeda |
| author_facet | Mikiko Nishioka Tadashi Maezawa Hiroki Takeuchi Katsuyuki Hagiwara Sachiyo Tarui Mito Sakamoto Erina Takayama Hideaki Yajima Eiji Kondo Hiroaki Kawato Hiroyuki Minoura Ken Sugaya Aisaku Fukuda Tomoaki Ikeda |
| author_sort | Mikiko Nishioka |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: A relationship between endometrial polypectomy and in vitro fertilization (IVF) pregnancy outcomes has been reported; however, only a few studies have compared polyp removal techniques and pregnancy rates. We investigated whether different polypectomy techniques with endometrial curettage and hysteroscopic polypectomy for endometrial polyps affect subsequent pregnancy outcomes. <i>Materials and Methods</i>: Data from 434 patients who had undergone polypectomy for suspected endometrial polyps using transvaginal ultrasonography before embryo transfer in IVF at four institutions between January 2017 and December 2020 were retrospectively analyzed. Overall, there were 157 and 277 patients in the hysteroscopic (mean age: 35.0 years) and curettage (mean age: 37.3 years) groups, respectively. Single-blastocyst transfer cases were selected from both groups and age-matched to unify background factors. <i>Results</i>: In the single-blastocyst transfer cases, 148 (mean age: 35.0 years) and 196 (mean age: 35.9 years) were in the hysteroscopic and curettage groups, respectively, with the 148 cases matched by age. In these cases, the pregnancy rates for the first embryo transfer were 68.2% (odds ratio (OR): 2.14) and 51.4% (OR: 1.06) in the hysteroscopic and curettage groups, respectively; the resulting OR was 2.03. The pregnancy rates after up to the second transfer were 80.4% (OR: 4.10) and 68.2% (OR: 2.14) in the hysteroscopic and curettage groups, respectively, in which the OR was 1.91. The live birth rates were 66.2% (OR: 1.956) and 53.4% (OR: 1.15) in the hysteroscopic and curettage groups, respectively, in which the odds ratio was 1.71. These results show the effectiveness of hysteroscopic endometrial polypectomy compared to polypectomy with endometrial curettage. No significant difference was found regarding the miscarriage rates between the two groups. <i>Conclusions</i>: Hysteroscopic endometrial polypectomy resulted in a higher pregnancy rate in subsequent embryo transfer than polypectomy with endometrial curettage. Therefore, establishing a facility where polypectomy can be performed hysteroscopically is crucial. |
| first_indexed | 2024-03-10T21:03:49Z |
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| id | doaj.art-a06a513059654f37b16215ee90d98448 |
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| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-10T21:03:49Z |
| publishDate | 2023-10-01 |
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| series | Medicina |
| spelling | doaj.art-a06a513059654f37b16215ee90d984482023-11-19T17:18:27ZengMDPI AGMedicina1010-660X1648-91442023-10-015910186810.3390/medicina59101868Pregnancy Rates after Hysteroscopic Endometrial Polypectomy versus Endometrial Curettage Polypectomy: A Retrospective StudyMikiko Nishioka0Tadashi Maezawa1Hiroki Takeuchi2Katsuyuki Hagiwara3Sachiyo Tarui4Mito Sakamoto5Erina Takayama6Hideaki Yajima7Eiji Kondo8Hiroaki Kawato9Hiroyuki Minoura10Ken Sugaya11Aisaku Fukuda12Tomoaki Ikeda13Department of Obstetrics and Gynecology, Graduate School of Medicine, Mie University, 2-174 Edo-bashi, Tsu, Mie 514-8507, JapanDepartment of Obstetrics and Gynecology, Mie University Hospital, 2-174 Edo-bashi, Tsu, Mie 514-8507, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medicine, Mie University, 2-174 Edo-bashi, Tsu, Mie 514-8507, JapanFaculty of Education, Mie University, 1577 Kurima-Machiya-cho, Tsu, Mie 514-8507, JapanDepartment of Obstetrics and Gynecology, IVF Osaka Clinic, 1-1-14 Nagatahigashi, Higashiosaka, Osaka 577-0012, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medicine, Mie University, 2-174 Edo-bashi, Tsu, Mie 514-8507, JapanDepartment of Obstetrics and Gynecology, Mie University Hospital, 2-174 Edo-bashi, Tsu, Mie 514-8507, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medicine, Mie University, 2-174 Edo-bashi, Tsu, Mie 514-8507, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medicine, Mie University, 2-174 Edo-bashi, Tsu, Mie 514-8507, JapanDepartment of Obstetrics and Gynecology, Kawato Ladies Clinic, 1-16-11 Betsumei, Yokkaichi, Mie 510-0007, JapanDepartment of Obstetrics and Gynecology, Minoura Ladies Clinic, 3-9-17 Isoyama, Suzuka, Mie 510-0256, JapanDepartment of Obstetrics and Gynecology, Saiseikai Matsusaka General Hospital, 15-6 asahimachiichiku, Matsusaka, Mie 515-8557, JapanDepartment of Obstetrics and Gynecology, IVF Osaka Clinic, 1-1-14 Nagatahigashi, Higashiosaka, Osaka 577-0012, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medicine, Mie University, 2-174 Edo-bashi, Tsu, Mie 514-8507, Japan<i>Background and Objectives</i>: A relationship between endometrial polypectomy and in vitro fertilization (IVF) pregnancy outcomes has been reported; however, only a few studies have compared polyp removal techniques and pregnancy rates. We investigated whether different polypectomy techniques with endometrial curettage and hysteroscopic polypectomy for endometrial polyps affect subsequent pregnancy outcomes. <i>Materials and Methods</i>: Data from 434 patients who had undergone polypectomy for suspected endometrial polyps using transvaginal ultrasonography before embryo transfer in IVF at four institutions between January 2017 and December 2020 were retrospectively analyzed. Overall, there were 157 and 277 patients in the hysteroscopic (mean age: 35.0 years) and curettage (mean age: 37.3 years) groups, respectively. Single-blastocyst transfer cases were selected from both groups and age-matched to unify background factors. <i>Results</i>: In the single-blastocyst transfer cases, 148 (mean age: 35.0 years) and 196 (mean age: 35.9 years) were in the hysteroscopic and curettage groups, respectively, with the 148 cases matched by age. In these cases, the pregnancy rates for the first embryo transfer were 68.2% (odds ratio (OR): 2.14) and 51.4% (OR: 1.06) in the hysteroscopic and curettage groups, respectively; the resulting OR was 2.03. The pregnancy rates after up to the second transfer were 80.4% (OR: 4.10) and 68.2% (OR: 2.14) in the hysteroscopic and curettage groups, respectively, in which the OR was 1.91. The live birth rates were 66.2% (OR: 1.956) and 53.4% (OR: 1.15) in the hysteroscopic and curettage groups, respectively, in which the odds ratio was 1.71. These results show the effectiveness of hysteroscopic endometrial polypectomy compared to polypectomy with endometrial curettage. No significant difference was found regarding the miscarriage rates between the two groups. <i>Conclusions</i>: Hysteroscopic endometrial polypectomy resulted in a higher pregnancy rate in subsequent embryo transfer than polypectomy with endometrial curettage. Therefore, establishing a facility where polypectomy can be performed hysteroscopically is crucial.https://www.mdpi.com/1648-9144/59/10/1868endometrial polypectomypregnancyIVF-ETsnarecurettage |
| spellingShingle | Mikiko Nishioka Tadashi Maezawa Hiroki Takeuchi Katsuyuki Hagiwara Sachiyo Tarui Mito Sakamoto Erina Takayama Hideaki Yajima Eiji Kondo Hiroaki Kawato Hiroyuki Minoura Ken Sugaya Aisaku Fukuda Tomoaki Ikeda Pregnancy Rates after Hysteroscopic Endometrial Polypectomy versus Endometrial Curettage Polypectomy: A Retrospective Study Medicina endometrial polypectomy pregnancy IVF-ET snare curettage |
| title | Pregnancy Rates after Hysteroscopic Endometrial Polypectomy versus Endometrial Curettage Polypectomy: A Retrospective Study |
| title_full | Pregnancy Rates after Hysteroscopic Endometrial Polypectomy versus Endometrial Curettage Polypectomy: A Retrospective Study |
| title_fullStr | Pregnancy Rates after Hysteroscopic Endometrial Polypectomy versus Endometrial Curettage Polypectomy: A Retrospective Study |
| title_full_unstemmed | Pregnancy Rates after Hysteroscopic Endometrial Polypectomy versus Endometrial Curettage Polypectomy: A Retrospective Study |
| title_short | Pregnancy Rates after Hysteroscopic Endometrial Polypectomy versus Endometrial Curettage Polypectomy: A Retrospective Study |
| title_sort | pregnancy rates after hysteroscopic endometrial polypectomy versus endometrial curettage polypectomy a retrospective study |
| topic | endometrial polypectomy pregnancy IVF-ET snare curettage |
| url | https://www.mdpi.com/1648-9144/59/10/1868 |
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