Pharmaceutical Benefits of Fluticasone Propionate Association to Delivery Systems: In Vitro and In Vivo Evaluation

Pharmaceutical Benefits of Fluticasone Propionate Association to Delivery Systems: In Vitro and In Vivo Evaluation

The objective of the present work was to characterize the ability of liposomes and cyclodextrin (CyD) complexes to modulate the in vivo profile of fluticasone (FTZ). In vitro cell compatibility tests were performed, exposing A549 cells to FTZ in the free form and FTZ associated to liposomes and comp...

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Bibliographic Details
Main Authors: Marina G. Dogbe, Ambinintsoa Yattussia Mafilaza, Carla Vânia Eleutério, Helena Cabral-Marques, Sandra Simões, Maria Manuela Gaspar
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Pharmaceutics
Subjects:
fluticasone propionate
pulmonary delivery
intranasal delivery
liposomes
cyclodextrins
in vivo studies
asthma murine model
Online Access:https://www.mdpi.com/1999-4923/11/10/521

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