Effects of dabigatran versus warfarin on 2-year cognitive outcomes in old patients with atrial fibrillation: results from the GIRAF randomized clinical trial

Effects of dabigatran versus warfarin on 2-year cognitive outcomes in old patients with atrial fibrillation: results from the GIRAF randomized clinical trial

Abstract Background Observational studies support a role for oral anticoagulation to reduce the risk of dementia in atrial fibrillation patients, but conclusive data are lacking. Since dabigatran offers a more stable anticoagulation, we hypothesized it would reduce cognitive decline when compared to...

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Bibliographic Details
Main Authors: Bruno Caramelli, Pai Ching Yu, Francisco A. M. Cardozo, Iuri R. Magalhães, Raphael R. Spera, Daniel K. Amado, Maria C. Escalante-Rojas, Danielle M. Gualandro, Daniela Calderaro, Caio A. M. Tavares, Flavio A. Borges-Junior, Adriana F. Pastana, Mariana G. Matheus, Sonia M. D. Brucki, Ana Carolina O. Rodrigues, Ricardo Nitrini, Paulo Caramelli
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Medicine
Subjects:
Atrial fibrillation
Dementia
Cognitive scores
Dabigatran
Warfarin
Elderly
Online Access:https://doi.org/10.1186/s12916-022-02563-2

Internet

https://doi.org/10.1186/s12916-022-02563-2

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