Role of Efflux in Antibiotic Resistance of Achromobacter xylosoxidans and Achromobacter insuavis Isolates From Patients With Cystic Fibrosis

Role of Efflux in Antibiotic Resistance of Achromobacter xylosoxidans and Achromobacter insuavis Isolates From Patients With Cystic Fibrosis

Achromobacter genus (including Achromobacter xylosoxidans, the most prevalent Achromobacter species in patients with cystic fibrosis) is poorly susceptible to most conventional antibiotics. Contribution of efflux by AxyABM, AxyXY-OprZ, and AxyEF-OprN and of target mutations were studied in clinical...

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Bibliographic Details
Main Authors: Hussein Chalhoub, Stefanie Kampmeier, Barbara C. Kahl, Françoise Van Bambeke
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Microbiology
Subjects:
Achromobacter
efflux
target mutation
macrolide
fluoroquinolone
aminoglycoside
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.762307/full

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