PANDAS – a rare but severe disorder associated with streptococcal infections; Awareness is needed

AbstractPANDAS is an acronym for ‘paediatric autoimmune neuropsychiatric disorders associated with streptococcal infections’ and is defined as a subgroup of PANS, ‘Paediatric acute-onset neuropsychiatric syndrome’. PANDAS is considered an autoimmune disease based on a streptococcal infection with a...

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Main Authors: Karin Frånlund, Charbél Talani
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Acta Oto-Laryngologica Case Reports
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/23772484.2023.2231146
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author Karin Frånlund
Charbél Talani
author_facet Karin Frånlund
Charbél Talani
author_sort Karin Frånlund
collection DOAJ
description AbstractPANDAS is an acronym for ‘paediatric autoimmune neuropsychiatric disorders associated with streptococcal infections’ and is defined as a subgroup of PANS, ‘Paediatric acute-onset neuropsychiatric syndrome’. PANDAS is considered an autoimmune disease based on a streptococcal infection with a verified immune response. The onset is often dramatic, with symptoms of OCD developing within 24-48 h. Symptoms include both psychological symptoms and physical symptoms. Treatments of PANDAS must address both physical and psychiatric symptoms. Supplemental treatments for PANDAS include tonsillectomy to prevent further streptococcal infections. We present a case of PANDAS with the aim of raising awareness of its diagnosis. PANDAS is a rare condition with an impact on the patient’s quality of life; thus, awareness is needed. A multidisciplinary team is needed for diagnosis and treatment. Otorhinolaryngologists may play an important role in the well-being of these patients when performing tonsillectomy.
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spelling doaj.art-a07aa587d6c44db2bc7ea15d16ef5e492024-03-25T14:56:39ZengTaylor & Francis GroupActa Oto-Laryngologica Case Reports2377-24842023-12-018110410710.1080/23772484.2023.2231146PANDAS – a rare but severe disorder associated with streptococcal infections; Awareness is neededKarin Frånlund0Charbél Talani1Faculty of Medicine and Health Sciences, Department of Biomedical and Clinical Sciences, Division of Sensory Organs and Communication, Linköping University, Linköping, SwedenFaculty of Medicine and Health Sciences, Department of Biomedical and Clinical Sciences, Division of Sensory Organs and Communication, Linköping University, Linköping, SwedenAbstractPANDAS is an acronym for ‘paediatric autoimmune neuropsychiatric disorders associated with streptococcal infections’ and is defined as a subgroup of PANS, ‘Paediatric acute-onset neuropsychiatric syndrome’. PANDAS is considered an autoimmune disease based on a streptococcal infection with a verified immune response. The onset is often dramatic, with symptoms of OCD developing within 24-48 h. Symptoms include both psychological symptoms and physical symptoms. Treatments of PANDAS must address both physical and psychiatric symptoms. Supplemental treatments for PANDAS include tonsillectomy to prevent further streptococcal infections. We present a case of PANDAS with the aim of raising awareness of its diagnosis. PANDAS is a rare condition with an impact on the patient’s quality of life; thus, awareness is needed. A multidisciplinary team is needed for diagnosis and treatment. Otorhinolaryngologists may play an important role in the well-being of these patients when performing tonsillectomy.https://www.tandfonline.com/doi/10.1080/23772484.2023.2231146PANSPANDASstreptococcal infectionpediatric autoimmune neuropsychiatric disorders
spellingShingle Karin Frånlund
Charbél Talani
PANDAS – a rare but severe disorder associated with streptococcal infections; Awareness is needed
Acta Oto-Laryngologica Case Reports
PANS
PANDAS
streptococcal infection
pediatric autoimmune neuropsychiatric disorders
title PANDAS – a rare but severe disorder associated with streptococcal infections; Awareness is needed
title_full PANDAS – a rare but severe disorder associated with streptococcal infections; Awareness is needed
title_fullStr PANDAS – a rare but severe disorder associated with streptococcal infections; Awareness is needed
title_full_unstemmed PANDAS – a rare but severe disorder associated with streptococcal infections; Awareness is needed
title_short PANDAS – a rare but severe disorder associated with streptococcal infections; Awareness is needed
title_sort pandas a rare but severe disorder associated with streptococcal infections awareness is needed
topic PANS
PANDAS
streptococcal infection
pediatric autoimmune neuropsychiatric disorders
url https://www.tandfonline.com/doi/10.1080/23772484.2023.2231146
work_keys_str_mv AT karinfranlund pandasararebutseveredisorderassociatedwithstreptococcalinfectionsawarenessisneeded
AT charbeltalani pandasararebutseveredisorderassociatedwithstreptococcalinfectionsawarenessisneeded