Association of Ultrapure Citicoline, Homotaurine and Vitamin E in the Management of Normotensive Glaucoma: A Case Report
Normal tension glaucoma (NTG) remains a therapeutic challenge for the ophthalmologist since there are no effective therapies as the main therapeutic target, i.e., the intraocular pressure (IOP) increase, is missed. We report on the effectiveness of two neuroprotective molecules (ultrapure citicoline...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2020-06-01
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| Series: | Case Reports in Ophthalmology |
| Subjects: | |
| Online Access: | https://www.karger.com/Article/FullText/507881 |
| _version_ | 1818209949267787776 |
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| author | Tommaso Verdina Nicola Passarelli Alessandra Carlini Francesca Chemello Rodolfo Mastropasqua Gian Maria Cavallini |
| author_facet | Tommaso Verdina Nicola Passarelli Alessandra Carlini Francesca Chemello Rodolfo Mastropasqua Gian Maria Cavallini |
| author_sort | Tommaso Verdina |
| collection | DOAJ |
| description | Normal tension glaucoma (NTG) remains a therapeutic challenge for the ophthalmologist since there are no effective therapies as the main therapeutic target, i.e., the intraocular pressure (IOP) increase, is missed. We report on the effectiveness of two neuroprotective molecules (ultrapure citicoline plus homotaurine), in combination with a topical hypotensive approach, in the management of NTG in a long-term follow-up (30 months). A 38-year-old Caucasian woman with no significant medical history and a diagnosis of NTG, after an extensive 30-month treatment with oral dietary supplement containing ultrapure citicoline 500 mg, homotaurine 50 mg and vitamin E once per day and topical glaucoma medication (brimonidine + brinzolamide drops twice per day), presented a significantly improved automated 24-2 visual field with a controlled tonometric measurement associated with a stabilization of retinal fiber layer and ganglion cells at OCT examination with patient satisfaction. This finding suggests that ultrapure citicoline together with homotaurine and vitamin E, through a synergistic neuroprotective effect, could be a promising approach in the management of NTG. |
| first_indexed | 2024-12-12T05:08:50Z |
| format | Article |
| id | doaj.art-a07b5d8a447c40d98f6c383eaf96cc09 |
| institution | Directory Open Access Journal |
| issn | 1663-2699 |
| language | English |
| last_indexed | 2024-12-12T05:08:50Z |
| publishDate | 2020-06-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Ophthalmology |
| spelling | doaj.art-a07b5d8a447c40d98f6c383eaf96cc092022-12-22T00:37:01ZengKarger PublishersCase Reports in Ophthalmology1663-26992020-06-0111222222810.1159/000507881507881Association of Ultrapure Citicoline, Homotaurine and Vitamin E in the Management of Normotensive Glaucoma: A Case ReportTommaso VerdinaNicola PassarelliAlessandra CarliniFrancesca ChemelloRodolfo MastropasquaGian Maria CavalliniNormal tension glaucoma (NTG) remains a therapeutic challenge for the ophthalmologist since there are no effective therapies as the main therapeutic target, i.e., the intraocular pressure (IOP) increase, is missed. We report on the effectiveness of two neuroprotective molecules (ultrapure citicoline plus homotaurine), in combination with a topical hypotensive approach, in the management of NTG in a long-term follow-up (30 months). A 38-year-old Caucasian woman with no significant medical history and a diagnosis of NTG, after an extensive 30-month treatment with oral dietary supplement containing ultrapure citicoline 500 mg, homotaurine 50 mg and vitamin E once per day and topical glaucoma medication (brimonidine + brinzolamide drops twice per day), presented a significantly improved automated 24-2 visual field with a controlled tonometric measurement associated with a stabilization of retinal fiber layer and ganglion cells at OCT examination with patient satisfaction. This finding suggests that ultrapure citicoline together with homotaurine and vitamin E, through a synergistic neuroprotective effect, could be a promising approach in the management of NTG.https://www.karger.com/Article/FullText/507881normotensive glaucomavisual fieldciticolinehomotaurineneuroprotection |
| spellingShingle | Tommaso Verdina Nicola Passarelli Alessandra Carlini Francesca Chemello Rodolfo Mastropasqua Gian Maria Cavallini Association of Ultrapure Citicoline, Homotaurine and Vitamin E in the Management of Normotensive Glaucoma: A Case Report Case Reports in Ophthalmology normotensive glaucoma visual field citicoline homotaurine neuroprotection |
| title | Association of Ultrapure Citicoline, Homotaurine and Vitamin E in the Management of Normotensive Glaucoma: A Case Report |
| title_full | Association of Ultrapure Citicoline, Homotaurine and Vitamin E in the Management of Normotensive Glaucoma: A Case Report |
| title_fullStr | Association of Ultrapure Citicoline, Homotaurine and Vitamin E in the Management of Normotensive Glaucoma: A Case Report |
| title_full_unstemmed | Association of Ultrapure Citicoline, Homotaurine and Vitamin E in the Management of Normotensive Glaucoma: A Case Report |
| title_short | Association of Ultrapure Citicoline, Homotaurine and Vitamin E in the Management of Normotensive Glaucoma: A Case Report |
| title_sort | association of ultrapure citicoline homotaurine and vitamin e in the management of normotensive glaucoma a case report |
| topic | normotensive glaucoma visual field citicoline homotaurine neuroprotection |
| url | https://www.karger.com/Article/FullText/507881 |
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