Pediatric gliosarcoma, a rare central nervous system tumor in children: Case report and literature review

Gliosarcoma is a rare and highly malignant central nervous system tumor that accounts for 1%–8% of glioblastomas; it usually occurs in middle-aged and older adults between 40 and 60 years of age and is rare in children. We report an 11-year-old boy with right frontal lobe gliosarcoma who underwent a...

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Main Authors: Jinyan Chen, Dong He, Gengyin Guo, Keke Zhang, Wenliang Sheng, Zhen Zhang
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023084128
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author Jinyan Chen
Dong He
Gengyin Guo
Keke Zhang
Wenliang Sheng
Zhen Zhang
author_facet Jinyan Chen
Dong He
Gengyin Guo
Keke Zhang
Wenliang Sheng
Zhen Zhang
author_sort Jinyan Chen
collection DOAJ
description Gliosarcoma is a rare and highly malignant central nervous system tumor that accounts for 1%–8% of glioblastomas; it usually occurs in middle-aged and older adults between 40 and 60 years of age and is rare in children. We report an 11-year-old boy with right frontal lobe gliosarcoma who underwent aggressive gross total resection and postoperative radiotherapy, experienced recurrence and subsequently underwent a second operation. To better understand the disease and explore treatment options, we briefly report this case and review the relevant literature.
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spelling doaj.art-a07f812d1a56413c9fd485ddc3b803da2023-12-02T07:01:27ZengElsevierHeliyon2405-84402023-11-01911e21204Pediatric gliosarcoma, a rare central nervous system tumor in children: Case report and literature reviewJinyan Chen0Dong He1Gengyin Guo2Keke Zhang3Wenliang Sheng4Zhen Zhang5Department of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, ChinaDepartment of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, ChinaDepartment of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, ChinaDepartment of Otolaryngology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, ChinaDepartment of Neurosurgery, Juxian People's Hospital, Rizhao, Shandong, ChinaDepartment of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China; Corresponding author.Gliosarcoma is a rare and highly malignant central nervous system tumor that accounts for 1%–8% of glioblastomas; it usually occurs in middle-aged and older adults between 40 and 60 years of age and is rare in children. We report an 11-year-old boy with right frontal lobe gliosarcoma who underwent aggressive gross total resection and postoperative radiotherapy, experienced recurrence and subsequently underwent a second operation. To better understand the disease and explore treatment options, we briefly report this case and review the relevant literature.http://www.sciencedirect.com/science/article/pii/S2405844023084128GliosarcomaGlioblastomaCerebral hemispheresPediatricSurgery
spellingShingle Jinyan Chen
Dong He
Gengyin Guo
Keke Zhang
Wenliang Sheng
Zhen Zhang
Pediatric gliosarcoma, a rare central nervous system tumor in children: Case report and literature review
Heliyon
Gliosarcoma
Glioblastoma
Cerebral hemispheres
Pediatric
Surgery
title Pediatric gliosarcoma, a rare central nervous system tumor in children: Case report and literature review
title_full Pediatric gliosarcoma, a rare central nervous system tumor in children: Case report and literature review
title_fullStr Pediatric gliosarcoma, a rare central nervous system tumor in children: Case report and literature review
title_full_unstemmed Pediatric gliosarcoma, a rare central nervous system tumor in children: Case report and literature review
title_short Pediatric gliosarcoma, a rare central nervous system tumor in children: Case report and literature review
title_sort pediatric gliosarcoma a rare central nervous system tumor in children case report and literature review
topic Gliosarcoma
Glioblastoma
Cerebral hemispheres
Pediatric
Surgery
url http://www.sciencedirect.com/science/article/pii/S2405844023084128
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