Toward the clinical application of the Child Psychosis-Risk Screening System (CPSS)

Introduction In our previous study, we have developed the Child Psychosis-risk Screening System (CPSS), which incorporates psychological and behavioral characteristics of childhood into an algorithm, based on a retrospective survey. Objectives In this study, we actually tried to evaluate the risk...

Full description

Bibliographic Details
Main Authors: Y. Hamasaki, M. Matsuo, Y. Sakaue, R. Sanada, T. Nakayama, S. Michikoshi, S. Ueba, N. Kurimoto, T. Hikida
Format: Article
Language:English
Published: Cambridge University Press 2022-06-01
Series:European Psychiatry
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S0924933822005855/type/journal_article
_version_ 1827754747483914240
author Y. Hamasaki
M. Matsuo
Y. Sakaue
R. Sanada
T. Nakayama
S. Michikoshi
S. Ueba
N. Kurimoto
T. Hikida
author_facet Y. Hamasaki
M. Matsuo
Y. Sakaue
R. Sanada
T. Nakayama
S. Michikoshi
S. Ueba
N. Kurimoto
T. Hikida
author_sort Y. Hamasaki
collection DOAJ
description Introduction In our previous study, we have developed the Child Psychosis-risk Screening System (CPSS), which incorporates psychological and behavioral characteristics of childhood into an algorithm, based on a retrospective survey. Objectives In this study, we actually tried to evaluate the risk of psychosis in pediatric and psychiatric outpatients using the CPSS. Methods We conducted an epidemiological study of 323 outpatients aged 6-18 years visiting pediatric and psychiatric departments using CBCL and clinical data (sex, age, winter birth, chief complaint, diagnosis, abuse, bullying, hikikomori). ROC analysis was used to assess the accuracy of CPSS predictions. Cross-sectional logistic regression analysis was performed on the clinical data to identify factors associated with risk groups exceeding the cutoff value. Results The results of the ROC analysis showed that the AUC (Area under the ROC Curve) was 80.3%, indicating that the CPSS has Moderate accuracy. The cutoff value was 98.11% (sensitivity: 0.857, specificity: 0.835), and 18% of the subjects were identified as risk groups above this value. Cross-sectional logistic regression analysis showed that schizophrenia diagnosis, no abuse, winter birth, and hikikomori were associated with the risk group, with respective odds ratios of 22.88, 10.76, 1.91, and 1.37. Conclusions The results of this study suggest that the CPSS can be applied to pediatric practice for early detection of risk for psychosis. The risk group is also present among pediatric patients with physical chief complaints. The factors suggested to be associated with risk groups may reflect the factors acting on the critical period of psychosis onset and the dynamic state. Disclosure No significant relationships.
first_indexed 2024-03-11T07:53:46Z
format Article
id doaj.art-a07fadfe0a0d4c0d97552693ab2453e0
institution Directory Open Access Journal
issn 0924-9338
1778-3585
language English
last_indexed 2024-03-11T07:53:46Z
publishDate 2022-06-01
publisher Cambridge University Press
record_format Article
series European Psychiatry
spelling doaj.art-a07fadfe0a0d4c0d97552693ab2453e02023-11-17T05:06:09ZengCambridge University PressEuropean Psychiatry0924-93381778-35852022-06-0165S225S22510.1192/j.eurpsy.2022.585Toward the clinical application of the Child Psychosis-Risk Screening System (CPSS)Y. Hamasaki0M. Matsuo1Y. Sakaue2R. Sanada3T. Nakayama4S. Michikoshi5S. Ueba6N. Kurimoto7T. Hikida8Kyoto Women’s University, Faculty Of Contemporary Society, kyoto, JapanShiga University of Medical Science, Department Of Psychiatry, Otsu、Shiga, JapanShiga University of Medical Science, Department Of Pediatrics, Otsu, Shiga, JapanShiga University of Medical Science, Department Of Psychiatry, Otsu、Shiga, JapanKyoto Women’s University, Faculty Of Contemporary Society, kyoto, JapanKyoto Women’s University, Faculty Of Contemporary Society, kyoto, JapanSaiseikai Moriyama Municipal Hospital, Department Of Pediatrics, Shiga, JapanShiga University of Medical Science, Department Of Psychiatry, Otsu、Shiga, Japan Shigasato Hospital, Department Of Psychiatry, Shiga, JapanOsaka University, Laboratory For Advanced Brain Functions, Institute For Protein Research, Osaka, Japan Introduction In our previous study, we have developed the Child Psychosis-risk Screening System (CPSS), which incorporates psychological and behavioral characteristics of childhood into an algorithm, based on a retrospective survey. Objectives In this study, we actually tried to evaluate the risk of psychosis in pediatric and psychiatric outpatients using the CPSS. Methods We conducted an epidemiological study of 323 outpatients aged 6-18 years visiting pediatric and psychiatric departments using CBCL and clinical data (sex, age, winter birth, chief complaint, diagnosis, abuse, bullying, hikikomori). ROC analysis was used to assess the accuracy of CPSS predictions. Cross-sectional logistic regression analysis was performed on the clinical data to identify factors associated with risk groups exceeding the cutoff value. Results The results of the ROC analysis showed that the AUC (Area under the ROC Curve) was 80.3%, indicating that the CPSS has Moderate accuracy. The cutoff value was 98.11% (sensitivity: 0.857, specificity: 0.835), and 18% of the subjects were identified as risk groups above this value. Cross-sectional logistic regression analysis showed that schizophrenia diagnosis, no abuse, winter birth, and hikikomori were associated with the risk group, with respective odds ratios of 22.88, 10.76, 1.91, and 1.37. Conclusions The results of this study suggest that the CPSS can be applied to pediatric practice for early detection of risk for psychosis. The risk group is also present among pediatric patients with physical chief complaints. The factors suggested to be associated with risk groups may reflect the factors acting on the critical period of psychosis onset and the dynamic state. Disclosure No significant relationships. https://www.cambridge.org/core/product/identifier/S0924933822005855/type/journal_articleChild Behavior ChecklistPsychosisCPSSprodrome
spellingShingle Y. Hamasaki
M. Matsuo
Y. Sakaue
R. Sanada
T. Nakayama
S. Michikoshi
S. Ueba
N. Kurimoto
T. Hikida
Toward the clinical application of the Child Psychosis-Risk Screening System (CPSS)
European Psychiatry
Child Behavior Checklist
Psychosis
CPSS
prodrome
title Toward the clinical application of the Child Psychosis-Risk Screening System (CPSS)
title_full Toward the clinical application of the Child Psychosis-Risk Screening System (CPSS)
title_fullStr Toward the clinical application of the Child Psychosis-Risk Screening System (CPSS)
title_full_unstemmed Toward the clinical application of the Child Psychosis-Risk Screening System (CPSS)
title_short Toward the clinical application of the Child Psychosis-Risk Screening System (CPSS)
title_sort toward the clinical application of the child psychosis risk screening system cpss
topic Child Behavior Checklist
Psychosis
CPSS
prodrome
url https://www.cambridge.org/core/product/identifier/S0924933822005855/type/journal_article
work_keys_str_mv AT yhamasaki towardtheclinicalapplicationofthechildpsychosisriskscreeningsystemcpss
AT mmatsuo towardtheclinicalapplicationofthechildpsychosisriskscreeningsystemcpss
AT ysakaue towardtheclinicalapplicationofthechildpsychosisriskscreeningsystemcpss
AT rsanada towardtheclinicalapplicationofthechildpsychosisriskscreeningsystemcpss
AT tnakayama towardtheclinicalapplicationofthechildpsychosisriskscreeningsystemcpss
AT smichikoshi towardtheclinicalapplicationofthechildpsychosisriskscreeningsystemcpss
AT sueba towardtheclinicalapplicationofthechildpsychosisriskscreeningsystemcpss
AT nkurimoto towardtheclinicalapplicationofthechildpsychosisriskscreeningsystemcpss
AT thikida towardtheclinicalapplicationofthechildpsychosisriskscreeningsystemcpss