The X-linked histone demethylases KDM5C and KDM6A as regulators of T cell-driven autoimmunity in the central nervous system

T cell-driven autoimmune responses are subject to striking sex-dependent effects. While the contributions of sex hormones are well-understood, those of sex chromosomes are meeting with increased appreciation. Here, we outline what is known about the contribution of sex chromosome-linked factors to e...

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Bibliographic Details
Main Authors: Mohamed Reda Fazazi, Gian Filippo Ruda, Paul E. Brennan, Manu Rangachari
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Brain Research Bulletin
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923023001739