Indapamide Increases IRS1 Expression and Modifies Adiponectin/NLRP3/PPARγ Crosstalk in Type 2 Diabetic Rats

Indapamide Increases IRS1 Expression and Modifies Adiponectin/NLRP3/PPARγ Crosstalk in Type 2 Diabetic Rats

The current study aimed to evaluate the anti-diabetic effects of canagliflozin (CANA) and indapamide (INDA) and their impacts as adiponectin modulators in experimentally induced type 2 diabetes mellitus (T2DM). T2DM was associated with a significant rise in blood glucose level and HbA1C%, andreduced...

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Bibliographic Details
Main Authors: Mahmoud M. Samaha, Manar G. Helal, Mohamed El-Sherbiny, Eman Said, Hatem A. Salem
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Antioxidants
Subjects:
canagliflozin
indapamide
adiponectin
NLRP3
PPARγ
IRS1
Online Access:https://www.mdpi.com/2076-3921/11/4/691

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