A Splenic Marginal Zone Lymphoma Case Presenting with Cyanosis, Spider Angiomas, and Polycythemia
Splenic marginal zone lymphoma (SMZL) is an indolent cancer classified among low-grade B-cell lymphomas in the World Health Organization (WHO) classification. The major characteristics of SMZL are splenomegaly, villous cytoplasmic protrusions of the lymphocytes in peripheral blood, anemia, and/or th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2015-12-01
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| Series: | İstanbul Medical Journal |
| Subjects: | |
| Online Access: |
http://imj.galenos.com.tr/archives/archive-detail/article-preview/a-splenic-marginal-zone-lymphoma-case-presenting-w/20931
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| Summary: | Splenic marginal zone lymphoma (SMZL) is an indolent cancer classified among low-grade B-cell lymphomas in the World Health Organization (WHO) classification. The major characteristics of SMZL are splenomegaly, villous cytoplasmic protrusions of the lymphocytes in peripheral blood, anemia, and/or thrombocytopenia. The involvement of various organs, particularly the bone marrow or liver, can be frequently observed. SMZL has been reported to be associated with hepatitis C infection. The course of the disease is generally indolent, but aggressive behavior may be observed in a minority of patients. Here, we report a 43-year-old male hepatitis B virus carrier who presented with abdominal distension, multiple spider angiomas on the skin, and central cyanosis, leading to a diagnosis of SMZL. |
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| ISSN: | 2619-9793 2148-094X |