A Splenic Marginal Zone Lymphoma Case Presenting with Cyanosis, Spider Angiomas, and Polycythemia

Splenic marginal zone lymphoma (SMZL) is an indolent cancer classified among low-grade B-cell lymphomas in the World Health Organization (WHO) classification. The major characteristics of SMZL are splenomegaly, villous cytoplasmic protrusions of the lymphocytes in peripheral blood, anemia, and/or th...

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Main Authors: Esma Güldal Altunoğlu, Muhlis Cem Ar, Nükhet Tüzüner, Kaya Sarıbeyoğlu
Format: Article
Language:English
Published: Galenos Yayinevi 2015-12-01
Series:İstanbul Medical Journal
Subjects:
Online Access: http://imj.galenos.com.tr/archives/archive-detail/article-preview/a-splenic-marginal-zone-lymphoma-case-presenting-w/20931
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author Esma Güldal Altunoğlu
Muhlis Cem Ar
Nükhet Tüzüner
Kaya Sarıbeyoğlu
author_facet Esma Güldal Altunoğlu
Muhlis Cem Ar
Nükhet Tüzüner
Kaya Sarıbeyoğlu
author_sort Esma Güldal Altunoğlu
collection DOAJ
description Splenic marginal zone lymphoma (SMZL) is an indolent cancer classified among low-grade B-cell lymphomas in the World Health Organization (WHO) classification. The major characteristics of SMZL are splenomegaly, villous cytoplasmic protrusions of the lymphocytes in peripheral blood, anemia, and/or thrombocytopenia. The involvement of various organs, particularly the bone marrow or liver, can be frequently observed. SMZL has been reported to be associated with hepatitis C infection. The course of the disease is generally indolent, but aggressive behavior may be observed in a minority of patients. Here, we report a 43-year-old male hepatitis B virus carrier who presented with abdominal distension, multiple spider angiomas on the skin, and central cyanosis, leading to a diagnosis of SMZL.
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spelling doaj.art-a086bc14a79b4e11a31dc4feb1923fbf2023-02-15T16:21:25ZengGalenos Yayineviİstanbul Medical Journal2619-97932148-094X2015-12-0116415816110.5152/imj.2015.3823313049054A Splenic Marginal Zone Lymphoma Case Presenting with Cyanosis, Spider Angiomas, and PolycythemiaEsma Güldal Altunoğlu0Muhlis Cem Ar1Nükhet Tüzüner2Kaya Sarıbeyoğlu3 Clinic of Internal Medicine, İstanbul Training and Research Hospital, İstanbul, Türkiye Division of Hematology, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul, Türkiye Division of Pathology, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul, Türkiye Department of General Surgery, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul, Türkiye Splenic marginal zone lymphoma (SMZL) is an indolent cancer classified among low-grade B-cell lymphomas in the World Health Organization (WHO) classification. The major characteristics of SMZL are splenomegaly, villous cytoplasmic protrusions of the lymphocytes in peripheral blood, anemia, and/or thrombocytopenia. The involvement of various organs, particularly the bone marrow or liver, can be frequently observed. SMZL has been reported to be associated with hepatitis C infection. The course of the disease is generally indolent, but aggressive behavior may be observed in a minority of patients. Here, we report a 43-year-old male hepatitis B virus carrier who presented with abdominal distension, multiple spider angiomas on the skin, and central cyanosis, leading to a diagnosis of SMZL. http://imj.galenos.com.tr/archives/archive-detail/article-preview/a-splenic-marginal-zone-lymphoma-case-presenting-w/20931 Splenic marginal zone lymphomacyanosisspider angioma
spellingShingle Esma Güldal Altunoğlu
Muhlis Cem Ar
Nükhet Tüzüner
Kaya Sarıbeyoğlu
A Splenic Marginal Zone Lymphoma Case Presenting with Cyanosis, Spider Angiomas, and Polycythemia
İstanbul Medical Journal
Splenic marginal zone lymphoma
cyanosis
spider angioma
title A Splenic Marginal Zone Lymphoma Case Presenting with Cyanosis, Spider Angiomas, and Polycythemia
title_full A Splenic Marginal Zone Lymphoma Case Presenting with Cyanosis, Spider Angiomas, and Polycythemia
title_fullStr A Splenic Marginal Zone Lymphoma Case Presenting with Cyanosis, Spider Angiomas, and Polycythemia
title_full_unstemmed A Splenic Marginal Zone Lymphoma Case Presenting with Cyanosis, Spider Angiomas, and Polycythemia
title_short A Splenic Marginal Zone Lymphoma Case Presenting with Cyanosis, Spider Angiomas, and Polycythemia
title_sort splenic marginal zone lymphoma case presenting with cyanosis spider angiomas and polycythemia
topic Splenic marginal zone lymphoma
cyanosis
spider angioma
url http://imj.galenos.com.tr/archives/archive-detail/article-preview/a-splenic-marginal-zone-lymphoma-case-presenting-w/20931
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