Seroprevalence of Anti-SARS-CoV-2 IgG Antibody in Healthcare Workers: A Report From Rafsanjan City
Background: Healthcare workers (HCWs) have a high risk of catching SARS-CoV-2 infection. Seroprevalence studies can provide related data on HCWs with a history of infections. Despite numerous seroepidemiological reports of COVID-19 in different groups, there are no such reports for HCWs working in R...
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| Format: | Article |
| Language: | fas |
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Qazvin University of Medical Sciences & Health Services
2022-03-01
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| Series: | The Journal of Qazvin University of Medical Sciences |
| Subjects: | |
| Online Access: | https://journal.qums.ac.ir/article-1-3277-en.html |
| _version_ | 1811175414466347008 |
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| author | Mahnaz Tashakori Ahmad Jamalizadeh Mohsen Nejad-Ghaderi Maryam Hadavi Aliakbar Yousefi-Ahmadipour Fatemeh Mohseni Moghadam Athareh Soresrafil Kazem Mashayekhi |
| author_facet | Mahnaz Tashakori Ahmad Jamalizadeh Mohsen Nejad-Ghaderi Maryam Hadavi Aliakbar Yousefi-Ahmadipour Fatemeh Mohseni Moghadam Athareh Soresrafil Kazem Mashayekhi |
| author_sort | Mahnaz Tashakori |
| collection | DOAJ |
| description | Background: Healthcare workers (HCWs) have a high risk of catching SARS-CoV-2 infection. Seroprevalence studies can provide related data on HCWs with a history of infections. Despite numerous seroepidemiological reports of COVID-19 in different groups, there are no such reports for HCWs working in Rafsanjan City, Iran. This study aimed to determine the SARS-CoV-2 seroprevalence among HCWs.
Methods: Blood samples were obtained from 295 participants, including healthcare personnel and administrative staff. The SARS-CoV-2 IgG antibody was measured by the ELISA method, and the obtained data were analyzed with the Chi-square test and logistic regression. A P<0.05 was considered statistically significant.
Results: The previous exposure to COVID-19 was higher in HCWs than in administrative department staff. Fifteen out of 130 (11.5%) participants had experienced SARS-CoV-2 infection without any symptoms. The results of logistic regression indicated that traveling (OR: 018, 95% CI: 0.08–0.74, P=0.001), occupation (OR: 0.2, 95% CI: 0.01–0.94, P<0.05), history of respiratory problems (OR: 0.15, 95% CI: 0.01–1.94, P<0.05), and major clinical signs (OR: 8.09, 95% CI: 3.7-17.66, P<0.001) are important factors which affect SARS-CoV-2 IgG antibodies.
Conclusion: Our results indicated an occupational risk for SARS-CoV-2 infection among HCWs. Because some HCWs are asymptomatic, their communication, such as traveling, must be controlled, and it is necessary to ensure the safety of HCWs and reduce their transfer to the community and patients. |
| first_indexed | 2024-04-10T19:35:47Z |
| format | Article |
| id | doaj.art-a087e624daf947e39613fef502f0971c |
| institution | Directory Open Access Journal |
| issn | 1561-3666 2228-7213 |
| language | fas |
| last_indexed | 2024-04-10T19:35:47Z |
| publishDate | 2022-03-01 |
| publisher | Qazvin University of Medical Sciences & Health Services |
| record_format | Article |
| series | The Journal of Qazvin University of Medical Sciences |
| spelling | doaj.art-a087e624daf947e39613fef502f0971c2023-01-30T05:40:42ZfasQazvin University of Medical Sciences & Health ServicesThe Journal of Qazvin University of Medical Sciences1561-36662228-72132022-03-0125420321010.32598/JID.25.4.4Seroprevalence of Anti-SARS-CoV-2 IgG Antibody in Healthcare Workers: A Report From Rafsanjan CityMahnaz Tashakori0 Ahmad Jamalizadeh1Mohsen Nejad-Ghaderi2Maryam Hadavi3Aliakbar Yousefi-Ahmadipour4Fatemeh Mohseni Moghadam5Athareh Soresrafil6Kazem Mashayekhi7Department of Laboratory Sciences, Faculty of Paramedicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.Non-communicable Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.Non-communicable Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.Department of Anesthesiology, Paramedical School, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.Department of Laboratory Sciences, Faculty of Paramedicine, Rafsanjan University of Medical Sciences, Rafsanjan, IranDepartment of Laboratory Sciences, Faculty of Paramedicine, Rafsanjan University of Medical Sciences, Rafsanjan, IranDepartment of Laboratory Sciences, Faculty of Paramedicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.Immunology of Infectious Diseases Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.Background: Healthcare workers (HCWs) have a high risk of catching SARS-CoV-2 infection. Seroprevalence studies can provide related data on HCWs with a history of infections. Despite numerous seroepidemiological reports of COVID-19 in different groups, there are no such reports for HCWs working in Rafsanjan City, Iran. This study aimed to determine the SARS-CoV-2 seroprevalence among HCWs. Methods: Blood samples were obtained from 295 participants, including healthcare personnel and administrative staff. The SARS-CoV-2 IgG antibody was measured by the ELISA method, and the obtained data were analyzed with the Chi-square test and logistic regression. A P<0.05 was considered statistically significant. Results: The previous exposure to COVID-19 was higher in HCWs than in administrative department staff. Fifteen out of 130 (11.5%) participants had experienced SARS-CoV-2 infection without any symptoms. The results of logistic regression indicated that traveling (OR: 018, 95% CI: 0.08–0.74, P=0.001), occupation (OR: 0.2, 95% CI: 0.01–0.94, P<0.05), history of respiratory problems (OR: 0.15, 95% CI: 0.01–1.94, P<0.05), and major clinical signs (OR: 8.09, 95% CI: 3.7-17.66, P<0.001) are important factors which affect SARS-CoV-2 IgG antibodies. Conclusion: Our results indicated an occupational risk for SARS-CoV-2 infection among HCWs. Because some HCWs are asymptomatic, their communication, such as traveling, must be controlled, and it is necessary to ensure the safety of HCWs and reduce their transfer to the community and patients.https://journal.qums.ac.ir/article-1-3277-en.htmlcovid-19sars-cov-2iggseroprevalencehealthcare worker |
| spellingShingle | Mahnaz Tashakori Ahmad Jamalizadeh Mohsen Nejad-Ghaderi Maryam Hadavi Aliakbar Yousefi-Ahmadipour Fatemeh Mohseni Moghadam Athareh Soresrafil Kazem Mashayekhi Seroprevalence of Anti-SARS-CoV-2 IgG Antibody in Healthcare Workers: A Report From Rafsanjan City The Journal of Qazvin University of Medical Sciences covid-19 sars-cov-2 igg seroprevalence healthcare worker |
| title | Seroprevalence of Anti-SARS-CoV-2 IgG Antibody in Healthcare Workers: A Report From Rafsanjan City |
| title_full | Seroprevalence of Anti-SARS-CoV-2 IgG Antibody in Healthcare Workers: A Report From Rafsanjan City |
| title_fullStr | Seroprevalence of Anti-SARS-CoV-2 IgG Antibody in Healthcare Workers: A Report From Rafsanjan City |
| title_full_unstemmed | Seroprevalence of Anti-SARS-CoV-2 IgG Antibody in Healthcare Workers: A Report From Rafsanjan City |
| title_short | Seroprevalence of Anti-SARS-CoV-2 IgG Antibody in Healthcare Workers: A Report From Rafsanjan City |
| title_sort | seroprevalence of anti sars cov 2 igg antibody in healthcare workers a report from rafsanjan city |
| topic | covid-19 sars-cov-2 igg seroprevalence healthcare worker |
| url | https://journal.qums.ac.ir/article-1-3277-en.html |
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