Structural, Optical, and Antibacterial Efficacy of Pure and Zinc-Doped Copper Oxide Against Pathogenic Bacteria

Copper oxide and Zinc (Zn)-doped Copper oxide nanostructures (CuO-NSs) are successfully synthesized by using a hydrothermal technique. The as-obtained pure and Zn-doped CuO-NSs were tested to study the effect of doping in CuO on structural, optical, and antibacterial properties. The band gap of the...

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Main Authors: Awais Khalid, Pervaiz Ahmad, Abdulrahman I. Alharthi, Saleh Muhammad, Mayeen Uddin Khandaker, Mubasher Rehman, Mohammad Rashed Iqbal Faruque, Israf Ud Din, Mshari A. Alotaibi, Khalid Alzimami, David A. Bradley
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Nanomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4991/11/2/451
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author Awais Khalid
Pervaiz Ahmad
Abdulrahman I. Alharthi
Saleh Muhammad
Mayeen Uddin Khandaker
Mubasher Rehman
Mohammad Rashed Iqbal Faruque
Israf Ud Din
Mshari A. Alotaibi
Khalid Alzimami
David A. Bradley
author_facet Awais Khalid
Pervaiz Ahmad
Abdulrahman I. Alharthi
Saleh Muhammad
Mayeen Uddin Khandaker
Mubasher Rehman
Mohammad Rashed Iqbal Faruque
Israf Ud Din
Mshari A. Alotaibi
Khalid Alzimami
David A. Bradley
author_sort Awais Khalid
collection DOAJ
description Copper oxide and Zinc (Zn)-doped Copper oxide nanostructures (CuO-NSs) are successfully synthesized by using a hydrothermal technique. The as-obtained pure and Zn-doped CuO-NSs were tested to study the effect of doping in CuO on structural, optical, and antibacterial properties. The band gap of the nanostructures is calculated by using the Tauc plot. Our results have shown that the band gap of CuO reduces with the addition of Zinc. Optimization of processing conditions and concentration of precursors leads to the formation of pine needles and sea urchin-like nanostructures. The antibacterial properties of obtained Zn-doped CuO-NSs are observed against Gram-negative <i>(Pseudomonas aeruginosa, Klebsiella pneumonia, Escherichia coli)</i> and Gram-positive <i>(Staphylococcus aureus)</i> bacteria via the agar well diffusion method. Zn doped s are found to have more effective bacterial resistance than pure CuO. The improved antibacterial activity is attributed to the reactive oxygen species (ROS) generation.
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spelling doaj.art-a0882f38ae524b008ca8a56651e6b8b82023-12-03T13:13:37ZengMDPI AGNanomaterials2079-49912021-02-0111245110.3390/nano11020451Structural, Optical, and Antibacterial Efficacy of Pure and Zinc-Doped Copper Oxide Against Pathogenic BacteriaAwais Khalid0Pervaiz Ahmad1Abdulrahman I. Alharthi2Saleh Muhammad3Mayeen Uddin Khandaker4Mubasher Rehman5Mohammad Rashed Iqbal Faruque6Israf Ud Din7Mshari A. Alotaibi8Khalid Alzimami9David A. Bradley10Department of Physics, Hazara University, Mansehra 21300, PakistanDepartment of Physics, University of Azad Jammu and Kashmir, Muzaffarabad 13100, PakistanDepartment of Chemistry, College of Science and Humanities, Prince Sattam Bin Abdulaziz University, P.O. Box 173, Al-Kharj 11942, Saudi ArabiaDepartment of Physics, Hazara University, Mansehra 21300, PakistanCenter for Applied Physics and Radiation Technologies, School of Engineering and Technology, Sunway University, Bandar Sunway 47500, Selangor, MalaysiaDepartment of Microbiology, Hazara University, Mansehra 21300, PakistanSpace Science Centre, Universiti Kebangsaan Malaysia (UKM), Bangi 43600, Selangor, MalaysiaDepartment of Chemistry, College of Science and Humanities, Prince Sattam Bin Abdulaziz University, P.O. Box 173, Al-Kharj 11942, Saudi ArabiaDepartment of Chemistry, College of Science and Humanities, Prince Sattam Bin Abdulaziz University, P.O. Box 173, Al-Kharj 11942, Saudi ArabiaDepartment of Radiological Sciences, College of Applied Medical Sciences, King Saud University, PO Box 10219, Riyadh 11433, Saudi ArabiaCenter for Applied Physics and Radiation Technologies, School of Engineering and Technology, Sunway University, Bandar Sunway 47500, Selangor, MalaysiaCopper oxide and Zinc (Zn)-doped Copper oxide nanostructures (CuO-NSs) are successfully synthesized by using a hydrothermal technique. The as-obtained pure and Zn-doped CuO-NSs were tested to study the effect of doping in CuO on structural, optical, and antibacterial properties. The band gap of the nanostructures is calculated by using the Tauc plot. Our results have shown that the band gap of CuO reduces with the addition of Zinc. Optimization of processing conditions and concentration of precursors leads to the formation of pine needles and sea urchin-like nanostructures. The antibacterial properties of obtained Zn-doped CuO-NSs are observed against Gram-negative <i>(Pseudomonas aeruginosa, Klebsiella pneumonia, Escherichia coli)</i> and Gram-positive <i>(Staphylococcus aureus)</i> bacteria via the agar well diffusion method. Zn doped s are found to have more effective bacterial resistance than pure CuO. The improved antibacterial activity is attributed to the reactive oxygen species (ROS) generation.https://www.mdpi.com/2079-4991/11/2/451copper oxidezinc-dopinghydrothermalantibacterial activity
spellingShingle Awais Khalid
Pervaiz Ahmad
Abdulrahman I. Alharthi
Saleh Muhammad
Mayeen Uddin Khandaker
Mubasher Rehman
Mohammad Rashed Iqbal Faruque
Israf Ud Din
Mshari A. Alotaibi
Khalid Alzimami
David A. Bradley
Structural, Optical, and Antibacterial Efficacy of Pure and Zinc-Doped Copper Oxide Against Pathogenic Bacteria
Nanomaterials
copper oxide
zinc-doping
hydrothermal
antibacterial activity
title Structural, Optical, and Antibacterial Efficacy of Pure and Zinc-Doped Copper Oxide Against Pathogenic Bacteria
title_full Structural, Optical, and Antibacterial Efficacy of Pure and Zinc-Doped Copper Oxide Against Pathogenic Bacteria
title_fullStr Structural, Optical, and Antibacterial Efficacy of Pure and Zinc-Doped Copper Oxide Against Pathogenic Bacteria
title_full_unstemmed Structural, Optical, and Antibacterial Efficacy of Pure and Zinc-Doped Copper Oxide Against Pathogenic Bacteria
title_short Structural, Optical, and Antibacterial Efficacy of Pure and Zinc-Doped Copper Oxide Against Pathogenic Bacteria
title_sort structural optical and antibacterial efficacy of pure and zinc doped copper oxide against pathogenic bacteria
topic copper oxide
zinc-doping
hydrothermal
antibacterial activity
url https://www.mdpi.com/2079-4991/11/2/451
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