Impact of Ergot Alkaloids on Female Reproduction in Domestic Livestock Species

Fescue toxicosis is a multifaceted syndrome that elicits many negative effects on livestock consuming ergot alkaloids produced by endophyte-infected tall fescue. The economic losses associated with fescue toxicosis are primarily due to reproductive failure including altered cyclicity, suppressed hor...

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Main Authors: Rebecca K. Poole, Daniel H. Poole
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/11/6/364
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author Rebecca K. Poole
Daniel H. Poole
author_facet Rebecca K. Poole
Daniel H. Poole
author_sort Rebecca K. Poole
collection DOAJ
description Fescue toxicosis is a multifaceted syndrome that elicits many negative effects on livestock consuming ergot alkaloids produced by endophyte-infected tall fescue. The economic losses associated with fescue toxicosis are primarily due to reproductive failure including altered cyclicity, suppressed hormone secretion, reduced pregnancy rates, agalactia, and reduced offspring birth weights. For decades, a multitude of research has investigated the physiological and cellular mechanisms of these reproductive failures associated with fescue toxicosis. This review will summarize the various effects of ergot alkaloids on female reproduction in grazing livestock species.
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spelling doaj.art-a08c97ef6c634d4e9862462f47b5fd6b2022-12-22T03:59:56ZengMDPI AGToxins2072-66512019-06-0111636410.3390/toxins11060364toxins11060364Impact of Ergot Alkaloids on Female Reproduction in Domestic Livestock SpeciesRebecca K. Poole0Daniel H. Poole1Department of Animal Science, North Carolina State University, Raleigh, NC 27607, USADepartment of Animal Science, North Carolina State University, Raleigh, NC 27607, USAFescue toxicosis is a multifaceted syndrome that elicits many negative effects on livestock consuming ergot alkaloids produced by endophyte-infected tall fescue. The economic losses associated with fescue toxicosis are primarily due to reproductive failure including altered cyclicity, suppressed hormone secretion, reduced pregnancy rates, agalactia, and reduced offspring birth weights. For decades, a multitude of research has investigated the physiological and cellular mechanisms of these reproductive failures associated with fescue toxicosis. This review will summarize the various effects of ergot alkaloids on female reproduction in grazing livestock species.https://www.mdpi.com/2072-6651/11/6/364ergot alkaloidslivestockreproduction
spellingShingle Rebecca K. Poole
Daniel H. Poole
Impact of Ergot Alkaloids on Female Reproduction in Domestic Livestock Species
Toxins
ergot alkaloids
livestock
reproduction
title Impact of Ergot Alkaloids on Female Reproduction in Domestic Livestock Species
title_full Impact of Ergot Alkaloids on Female Reproduction in Domestic Livestock Species
title_fullStr Impact of Ergot Alkaloids on Female Reproduction in Domestic Livestock Species
title_full_unstemmed Impact of Ergot Alkaloids on Female Reproduction in Domestic Livestock Species
title_short Impact of Ergot Alkaloids on Female Reproduction in Domestic Livestock Species
title_sort impact of ergot alkaloids on female reproduction in domestic livestock species
topic ergot alkaloids
livestock
reproduction
url https://www.mdpi.com/2072-6651/11/6/364
work_keys_str_mv AT rebeccakpoole impactofergotalkaloidsonfemalereproductionindomesticlivestockspecies
AT danielhpoole impactofergotalkaloidsonfemalereproductionindomesticlivestockspecies