(±)-((2<i>S</i>,5<i>R</i>)-5-(Acetoxymethyl)tetrahydrofuran-2-yl)methyl Benzoate

(±)-((2<i>S</i>,5<i>R</i>)-5-(Acetoxymethyl)tetrahydrofuran-2-yl)methyl Benzoate

In this note we report the synthesis of a doubly acylated <i>cis</i>-THF-diol product synthesised in three steps by the stereoselective RuO<sub>4</sub>-catalysed oxidative cyclisation of 1,5-hexadiene, followed by benzoylation and acetylation. This substance is one of the sub...

Full description

Bibliographic Details
Main Author: Vincenzo Piccialli
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Molbank
Subjects:
bis-acylated α-bis-hydroxymethyl-tetrahydrofuran
oxidative cyclization
<sup>1</sup>H-NMR
<sup>13</sup>C-NMR
FTIR
HRESIMS
Online Access:https://www.mdpi.com/1422-8599/2022/1/M1349
Description
Summary:In this note we report the synthesis of a doubly acylated <i>cis</i>-THF-diol product synthesised in three steps by the stereoselective RuO<sub>4</sub>-catalysed oxidative cyclisation of 1,5-hexadiene, followed by benzoylation and acetylation. This substance is one of the substrates chosen to probe a new developed oxidative procedure to transform bis-acylated THF-diols into bis-acylated 1,4-diketones. This new derivative was fully characterised by spectroscopic methods.
ISSN:1422-8599

Similar Items