Assessing the effects of artificial gravity in an analog of long-duration spaceflight: The protocol and implementation of the AGBRESA bed rest study
A comprehensive strategy is required to mitigate risks to astronauts’ health, well-being, and performance. This strategy includes developing countermeasures to prevent or reduce adverse responses to the stressors astronauts encounter during spaceflight, such as weightlessness. Because artificial gra...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Physiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2022.976926/full |
| _version_ | 1811275601829429248 |
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| author | Gilles Clément Jörn Rittweger Andrea Nitsche Wolfgang Doering Petra Frings-Meuthen Olga Hand Timo Frett Alexandra Noppe Freia Paulke Leopold Lecheler Jens Jordan Claudia Stern Edwin Mulder |
| author_facet | Gilles Clément Jörn Rittweger Andrea Nitsche Wolfgang Doering Petra Frings-Meuthen Olga Hand Timo Frett Alexandra Noppe Freia Paulke Leopold Lecheler Jens Jordan Claudia Stern Edwin Mulder |
| author_sort | Gilles Clément |
| collection | DOAJ |
| description | A comprehensive strategy is required to mitigate risks to astronauts’ health, well-being, and performance. This strategy includes developing countermeasures to prevent or reduce adverse responses to the stressors astronauts encounter during spaceflight, such as weightlessness. Because artificial gravity (AG) by centrifugation simultaneously affects all physiological systems, AG could mitigate the effects of weightlessness in multiple systems. In 2019, NASA and the German Aerospace Center conducted a 60-days Artificial Gravity Bed Rest Study with the European Space Agency (AGBRESA). The objectives of this study were to 1) determine if 30 min of AG daily is protective during head down bed rest, and 2) compare the protective effects of a single daily bout (30 min) of AG versus multiple daily bouts (6 × 5 min) of AG (1 Gz at the center of mass) on physiological functions that are affected by weightlessness and by head-down tilt bed rest. The AGBRESA study involved a comprehensive suite of standard and innovative technologies to characterize changes in a broad spectrum of physiological systems. The current article is intended to provide a detailed overview of the methods used during AGBRESA. |
| first_indexed | 2024-04-12T23:41:52Z |
| format | Article |
| id | doaj.art-a095aa3a21e4458e9d8bd7007afe8fed |
| institution | Directory Open Access Journal |
| issn | 1664-042X |
| language | English |
| last_indexed | 2024-04-12T23:41:52Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj.art-a095aa3a21e4458e9d8bd7007afe8fed2022-12-22T03:11:59ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2022-09-011310.3389/fphys.2022.976926976926Assessing the effects of artificial gravity in an analog of long-duration spaceflight: The protocol and implementation of the AGBRESA bed rest studyGilles Clément0Jörn Rittweger1Andrea Nitsche2Wolfgang Doering3Petra Frings-Meuthen4Olga Hand5Timo Frett6Alexandra Noppe7Freia Paulke8Leopold Lecheler9Jens Jordan10Claudia Stern11Edwin Mulder12KBR, Houston, TX, United StatesInstitute of Aerospace Medicine, German Aerospace Center, Cologne, GermanyInstitute of Aerospace Medicine, German Aerospace Center, Cologne, GermanyInstitute of Aerospace Medicine, German Aerospace Center, Cologne, GermanyInstitute of Aerospace Medicine, German Aerospace Center, Cologne, GermanyInstitute of Aerospace Medicine, German Aerospace Center, Cologne, GermanyInstitute of Aerospace Medicine, German Aerospace Center, Cologne, GermanyInstitute of Aerospace Medicine, German Aerospace Center, Cologne, GermanyInstitute of Aerospace Medicine, German Aerospace Center, Cologne, GermanyInstitute of Aerospace Medicine, German Aerospace Center, Cologne, GermanyInstitute of Aerospace Medicine, German Aerospace Center, Cologne, GermanyInstitute of Aerospace Medicine, German Aerospace Center, Cologne, GermanyInstitute of Aerospace Medicine, German Aerospace Center, Cologne, GermanyA comprehensive strategy is required to mitigate risks to astronauts’ health, well-being, and performance. This strategy includes developing countermeasures to prevent or reduce adverse responses to the stressors astronauts encounter during spaceflight, such as weightlessness. Because artificial gravity (AG) by centrifugation simultaneously affects all physiological systems, AG could mitigate the effects of weightlessness in multiple systems. In 2019, NASA and the German Aerospace Center conducted a 60-days Artificial Gravity Bed Rest Study with the European Space Agency (AGBRESA). The objectives of this study were to 1) determine if 30 min of AG daily is protective during head down bed rest, and 2) compare the protective effects of a single daily bout (30 min) of AG versus multiple daily bouts (6 × 5 min) of AG (1 Gz at the center of mass) on physiological functions that are affected by weightlessness and by head-down tilt bed rest. The AGBRESA study involved a comprehensive suite of standard and innovative technologies to characterize changes in a broad spectrum of physiological systems. The current article is intended to provide a detailed overview of the methods used during AGBRESA.https://www.frontiersin.org/articles/10.3389/fphys.2022.976926/fullbed restartificial gravityweightlessnesscountermeasuresanalogs |
| spellingShingle | Gilles Clément Jörn Rittweger Andrea Nitsche Wolfgang Doering Petra Frings-Meuthen Olga Hand Timo Frett Alexandra Noppe Freia Paulke Leopold Lecheler Jens Jordan Claudia Stern Edwin Mulder Assessing the effects of artificial gravity in an analog of long-duration spaceflight: The protocol and implementation of the AGBRESA bed rest study Frontiers in Physiology bed rest artificial gravity weightlessness countermeasures analogs |
| title | Assessing the effects of artificial gravity in an analog of long-duration spaceflight: The protocol and implementation of the AGBRESA bed rest study |
| title_full | Assessing the effects of artificial gravity in an analog of long-duration spaceflight: The protocol and implementation of the AGBRESA bed rest study |
| title_fullStr | Assessing the effects of artificial gravity in an analog of long-duration spaceflight: The protocol and implementation of the AGBRESA bed rest study |
| title_full_unstemmed | Assessing the effects of artificial gravity in an analog of long-duration spaceflight: The protocol and implementation of the AGBRESA bed rest study |
| title_short | Assessing the effects of artificial gravity in an analog of long-duration spaceflight: The protocol and implementation of the AGBRESA bed rest study |
| title_sort | assessing the effects of artificial gravity in an analog of long duration spaceflight the protocol and implementation of the agbresa bed rest study |
| topic | bed rest artificial gravity weightlessness countermeasures analogs |
| url | https://www.frontiersin.org/articles/10.3389/fphys.2022.976926/full |
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