Structure of the Helicobacter pylori Cag type IV secretion system

Structure of the Helicobacter pylori Cag type IV secretion system

Bacterial type IV secretion systems (T4SSs) are molecular machines that can mediate interbacterial DNA transfer through conjugation and delivery of effector molecules into host cells. The Helicobacter pylori Cag T4SS translocates CagA, a bacterial oncoprotein, into gastric cells, contributing to gas...

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Bibliographic Details
Main Authors: Jeong Min Chung, Michael J Sheedlo, Anne M Campbell, Neha Sawhney, Arwen E Frick-Cheng, Dana Borden Lacy, Timothy L Cover, Melanie D Ohi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-06-01
Series:eLife
Subjects:
Helicobacter pylori
Type IV secretion system
gastric cancer
cryo-electron microscopy
bacterial protein secretion
Online Access:https://elifesciences.org/articles/47644

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