Virtual Screening, Synthesis and Biological Evaluation of <i>Streptococcus mutans</i> Mediated Biofilm Inhibitors

Virtual Screening, Synthesis and Biological Evaluation of <i>Streptococcus mutans</i> Mediated Biofilm Inhibitors

Dental caries, a global oral health concern, is a biofilm-mediated disease. Streptococcus mutans, the most prevalent oral microbiota, produces extracellular enzymes, including glycosyltransferases responsible for sucrose polymerization. In bacterial communities, the biofilm matrix confers resistance...

Full description

Bibliographic Details
Main Authors: Lubna Atta, Ruqaiya Khalil, Khalid Mohammed Khan, Moatter Zehra, Faiza Saleem, Mohammad Nur-e-Alam, Zaheer Ul-Haq
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Molecules
Subjects:
dental caries
biofilm
glucosyltransferases
virtual screening
antibiofilm
antimicrobial ADMET profiling
Online Access:https://www.mdpi.com/1420-3049/27/4/1455

Internet

https://www.mdpi.com/1420-3049/27/4/1455

Similar Items