Insertion-deletion polymorphism of ACE gene and increased body mass among hypertensive patients from various ethnic groups in Mordovia Republic
Aim.To stuffy the association between insertion-deletion (ID) polymorphism of ACE gene and increased body mass (BM) among patients with arterial hypertension (AH), representing various ethnic groups of Mordovia Republic.Material and methods. In total, 295 patients with verified essential AH were exa...
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Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2009-12-01
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Series: | Кардиоваскулярная терапия и профилактика |
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Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1475 |
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author | L. N. Goncharova D. V. Biryukova Z. B. Khasanova E. I. Timoshkina O. N. Kuzovenkova S. V. Semenova V. A. Snegovskoy L. K. Fedotkina N. V. Konovalova A. Yu. Postnov |
author_facet | L. N. Goncharova D. V. Biryukova Z. B. Khasanova E. I. Timoshkina O. N. Kuzovenkova S. V. Semenova V. A. Snegovskoy L. K. Fedotkina N. V. Konovalova A. Yu. Postnov |
author_sort | L. N. Goncharova |
collection | DOAJ |
description | Aim.To stuffy the association between insertion-deletion (ID) polymorphism of ACE gene and increased body mass (BM) among patients with arterial hypertension (AH), representing various ethnic groups of Mordovia Republic.Material and methods. In total, 295 patients with verified essential AH were examined: 207 Mordovians and 88 Russians. The control group included 221 people: 147 Mordovians and 74 Russians. In all participants, anamnestic, clinical, laboratory, and instrumental examination was performed, including 12-lead electrocardiography, echocardiography, and assessment of ACE gene ID polymorphism.Results. It was demonstrated that higher BM index levels were registered in ID genotype carriers of either ethnicity more frequently, but not significantly.Conclusion.In both Mordovian and Russian patients with AH, no significant association was observed between ACE gene polymorphism and increased MT. |
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id | doaj.art-a0a39ea69a524193992a237b16421b37 |
institution | Directory Open Access Journal |
issn | 1728-8800 2619-0125 |
language | Russian |
last_indexed | 2024-04-10T03:38:37Z |
publishDate | 2009-12-01 |
publisher | «SILICEA-POLIGRAF» LLC |
record_format | Article |
series | Кардиоваскулярная терапия и профилактика |
spelling | doaj.art-a0a39ea69a524193992a237b16421b372023-03-13T07:23:17Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252009-12-0186591193Insertion-deletion polymorphism of ACE gene and increased body mass among hypertensive patients from various ethnic groups in Mordovia RepublicL. N. Goncharova0D. V. Biryukova1Z. B. Khasanova2E. I. Timoshkina3O. N. Kuzovenkova4S. V. Semenova5V. A. Snegovskoy6L. K. Fedotkina7N. V. Konovalova8A. Yu. Postnov9ГОУ ВПО Мордовский государственный университет имени Н.П. ОгареваГОУ ВПО Мордовский государственный университет имени Н.П. ОгареваФГУ Российский кардиологический научно-производственный комплекс РосмедтехнологииГОУ ВПО Мордовский государственный университет имени Н.П. ОгареваГОУ ВПО Мордовский государственный университет имени Н.П. ОгареваГОУ ВПО Мордовский государственный университет имени Н.П. ОгареваГОУ ВПО Мордовский государственный университет имени Н.П. ОгареваГОУ ВПО Мордовский государственный университет имени Н.П. ОгареваФГУ Российский кардиологический научно-производственный комплекс РосмедтехнологииФГУ Российский кардиологический научно-производственный комплекс РосмедтехнологииAim.To stuffy the association between insertion-deletion (ID) polymorphism of ACE gene and increased body mass (BM) among patients with arterial hypertension (AH), representing various ethnic groups of Mordovia Republic.Material and methods. In total, 295 patients with verified essential AH were examined: 207 Mordovians and 88 Russians. The control group included 221 people: 147 Mordovians and 74 Russians. In all participants, anamnestic, clinical, laboratory, and instrumental examination was performed, including 12-lead electrocardiography, echocardiography, and assessment of ACE gene ID polymorphism.Results. It was demonstrated that higher BM index levels were registered in ID genotype carriers of either ethnicity more frequently, but not significantly.Conclusion.In both Mordovian and Russian patients with AH, no significant association was observed between ACE gene polymorphism and increased MT.https://cardiovascular.elpub.ru/jour/article/view/1475артериальная гипертензияповышенная масса телаген ace |
spellingShingle | L. N. Goncharova D. V. Biryukova Z. B. Khasanova E. I. Timoshkina O. N. Kuzovenkova S. V. Semenova V. A. Snegovskoy L. K. Fedotkina N. V. Konovalova A. Yu. Postnov Insertion-deletion polymorphism of ACE gene and increased body mass among hypertensive patients from various ethnic groups in Mordovia Republic Кардиоваскулярная терапия и профилактика артериальная гипертензия повышенная масса тела ген ace |
title | Insertion-deletion polymorphism of ACE gene and increased body mass among hypertensive patients from various ethnic groups in Mordovia Republic |
title_full | Insertion-deletion polymorphism of ACE gene and increased body mass among hypertensive patients from various ethnic groups in Mordovia Republic |
title_fullStr | Insertion-deletion polymorphism of ACE gene and increased body mass among hypertensive patients from various ethnic groups in Mordovia Republic |
title_full_unstemmed | Insertion-deletion polymorphism of ACE gene and increased body mass among hypertensive patients from various ethnic groups in Mordovia Republic |
title_short | Insertion-deletion polymorphism of ACE gene and increased body mass among hypertensive patients from various ethnic groups in Mordovia Republic |
title_sort | insertion deletion polymorphism of ace gene and increased body mass among hypertensive patients from various ethnic groups in mordovia republic |
topic | артериальная гипертензия повышенная масса тела ген ace |
url | https://cardiovascular.elpub.ru/jour/article/view/1475 |
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