Insertion-deletion polymorphism of ACE gene and increased body mass among hypertensive patients from various ethnic groups in Mordovia Republic

Aim.To stuffy the association between insertion-deletion (ID) polymorphism of ACE gene and increased body mass (BM) among patients with arterial hypertension (AH), representing various ethnic groups of Mordovia Republic.Material and methods. In total, 295 patients with verified essential AH were exa...

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Main Authors: L. N. Goncharova, D. V. Biryukova, Z. B. Khasanova, E. I. Timoshkina, O. N. Kuzovenkova, S. V. Semenova, V. A. Snegovskoy, L. K. Fedotkina, N. V. Konovalova, A. Yu. Postnov
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2009-12-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/1475
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author L. N. Goncharova
D. V. Biryukova
Z. B. Khasanova
E. I. Timoshkina
O. N. Kuzovenkova
S. V. Semenova
V. A. Snegovskoy
L. K. Fedotkina
N. V. Konovalova
A. Yu. Postnov
author_facet L. N. Goncharova
D. V. Biryukova
Z. B. Khasanova
E. I. Timoshkina
O. N. Kuzovenkova
S. V. Semenova
V. A. Snegovskoy
L. K. Fedotkina
N. V. Konovalova
A. Yu. Postnov
author_sort L. N. Goncharova
collection DOAJ
description Aim.To stuffy the association between insertion-deletion (ID) polymorphism of ACE gene and increased body mass (BM) among patients with arterial hypertension (AH), representing various ethnic groups of Mordovia Republic.Material and methods. In total, 295 patients with verified essential AH were examined: 207 Mordovians and 88 Russians. The control group included 221 people: 147 Mordovians and 74 Russians. In all participants, anamnestic, clinical, laboratory, and instrumental examination was performed, including 12-lead electrocardiography, echocardiography, and assessment of ACE gene ID polymorphism.Results. It was demonstrated that higher BM index levels were registered in ID genotype carriers of either ethnicity more frequently, but not significantly.Conclusion.In both Mordovian and Russian patients with AH, no significant association was observed between ACE gene polymorphism and increased MT.
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spelling doaj.art-a0a39ea69a524193992a237b16421b372023-03-13T07:23:17Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252009-12-0186591193Insertion-deletion polymorphism of ACE gene and increased body mass among hypertensive patients from various ethnic groups in Mordovia RepublicL. N. Goncharova0D. V. Biryukova1Z. B. Khasanova2E. I. Timoshkina3O. N. Kuzovenkova4S. V. Semenova5V. A. Snegovskoy6L. K. Fedotkina7N. V. Konovalova8A. Yu. Postnov9ГОУ ВПО Мордовский государственный университет имени Н.П. ОгареваГОУ ВПО Мордовский государственный университет имени Н.П. ОгареваФГУ Российский кардиологический научно-производственный комплекс РосмедтехнологииГОУ ВПО Мордовский государственный университет имени Н.П. ОгареваГОУ ВПО Мордовский государственный университет имени Н.П. ОгареваГОУ ВПО Мордовский государственный университет имени Н.П. ОгареваГОУ ВПО Мордовский государственный университет имени Н.П. ОгареваГОУ ВПО Мордовский государственный университет имени Н.П. ОгареваФГУ Российский кардиологический научно-производственный комплекс РосмедтехнологииФГУ Российский кардиологический научно-производственный комплекс РосмедтехнологииAim.To stuffy the association between insertion-deletion (ID) polymorphism of ACE gene and increased body mass (BM) among patients with arterial hypertension (AH), representing various ethnic groups of Mordovia Republic.Material and methods. In total, 295 patients with verified essential AH were examined: 207 Mordovians and 88 Russians. The control group included 221 people: 147 Mordovians and 74 Russians. In all participants, anamnestic, clinical, laboratory, and instrumental examination was performed, including 12-lead electrocardiography, echocardiography, and assessment of ACE gene ID polymorphism.Results. It was demonstrated that higher BM index levels were registered in ID genotype carriers of either ethnicity more frequently, but not significantly.Conclusion.In both Mordovian and Russian patients with AH, no significant association was observed between ACE gene polymorphism and increased MT.https://cardiovascular.elpub.ru/jour/article/view/1475артериальная гипертензияповышенная масса телаген ace
spellingShingle L. N. Goncharova
D. V. Biryukova
Z. B. Khasanova
E. I. Timoshkina
O. N. Kuzovenkova
S. V. Semenova
V. A. Snegovskoy
L. K. Fedotkina
N. V. Konovalova
A. Yu. Postnov
Insertion-deletion polymorphism of ACE gene and increased body mass among hypertensive patients from various ethnic groups in Mordovia Republic
Кардиоваскулярная терапия и профилактика
артериальная гипертензия
повышенная масса тела
ген ace
title Insertion-deletion polymorphism of ACE gene and increased body mass among hypertensive patients from various ethnic groups in Mordovia Republic
title_full Insertion-deletion polymorphism of ACE gene and increased body mass among hypertensive patients from various ethnic groups in Mordovia Republic
title_fullStr Insertion-deletion polymorphism of ACE gene and increased body mass among hypertensive patients from various ethnic groups in Mordovia Republic
title_full_unstemmed Insertion-deletion polymorphism of ACE gene and increased body mass among hypertensive patients from various ethnic groups in Mordovia Republic
title_short Insertion-deletion polymorphism of ACE gene and increased body mass among hypertensive patients from various ethnic groups in Mordovia Republic
title_sort insertion deletion polymorphism of ace gene and increased body mass among hypertensive patients from various ethnic groups in mordovia republic
topic артериальная гипертензия
повышенная масса тела
ген ace
url https://cardiovascular.elpub.ru/jour/article/view/1475
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