Efficiency of Intravitreal Ranibizumab Injection in Wet Age-Related Macular Degeneration
Purpose: To evaluate the efficiency of the treatment of intravitreal ranibizumabin on the functions of lesion size and visual outcome in neovascular age-related macular degeneration cases. Material and Methods: Age-related macular degeneration diagnosis of 71eyes of 59 patients were analyzed retrosp...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Cukurova University
2015-12-01
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| Series: | Çukurova Üniversitesi Tıp Fakültesi Dergisi |
| Subjects: | |
| Online Access: | http://www.scopemed.org/fulltextpdf.php?mno=180917 |
| _version_ | 1797923552052117504 |
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| author | Didem sahin Ahmet sahin Adnan Aksoy Lokman Aslan Ali simsek |
| author_facet | Didem sahin Ahmet sahin Adnan Aksoy Lokman Aslan Ali simsek |
| author_sort | Didem sahin |
| collection | DOAJ |
| description | Purpose: To evaluate the efficiency of the treatment of intravitreal ranibizumabin on the functions of lesion size and visual outcome in neovascular age-related macular degeneration cases.
Material and Methods: Age-related macular degeneration diagnosis of 71eyes of 59 patients were analyzed retrospectively. Best-corrected visual acuity (BCVA), biomicroscopic examination, intra ocularpressure and fundus examinations were noted about the cases. In order to evaluate the effiency of IVR treatment, widest lesion diameter (WLD) of choroidal neovascularization (CNV) and BCVA were compared statistically, before and after treatment according to fundus fluorescein angiography (FFA).
Results: The mean follow-upperiod was 14+/-5 months. Snellen BCVA was found 0.13+/-0.09 before treatment and was found 0.22+/-0.16 after treatment according to Snellen. A statistically significant increase was detected in BCVA after IVR teatment. WLD was calculated 4040+/-117 and #956;m before treatment and 3620+/-128 and #956;m after treatment. After IVR treatment a statistically significant decrease was founded in WLD.
Conclusion: In our study, an increase in BCVA and a decrease in WLD were observed with the treatment of IVR in wet AMD cases. IVR was made out to be an effective and safe treatment. It can be thought that an obvious improvement was achieved acording to anatomic and visual acuity. [Cukurova Med J 2015; 40(4.000): 757-765] |
| first_indexed | 2024-04-10T14:49:12Z |
| format | Article |
| id | doaj.art-a0a62de3075744ce81a9dde0092ded60 |
| institution | Directory Open Access Journal |
| issn | 0250-5150 |
| language | English |
| last_indexed | 2024-04-10T14:49:12Z |
| publishDate | 2015-12-01 |
| publisher | Cukurova University |
| record_format | Article |
| series | Çukurova Üniversitesi Tıp Fakültesi Dergisi |
| spelling | doaj.art-a0a62de3075744ce81a9dde0092ded602023-02-15T16:07:41ZengCukurova UniversityÇukurova Üniversitesi Tıp Fakültesi Dergisi0250-51502015-12-01404757765180917Efficiency of Intravitreal Ranibizumab Injection in Wet Age-Related Macular DegenerationDidem sahin0Ahmet sahin1Adnan Aksoy2Lokman Aslan3Ali simsek4Corlu Devlet Hastanesi Goz Klinigi/ Corlu/ Tekirdag/ Turkiye Corlu Devlet Hastanesi Goz Klinigi/ Corlu/ Tekirdag/ Turkiye Kahramanmaras Sutcu imam Universitesi Tip Fakultesi Goz Klinigi/ Kahramanmaras/ Turkiye Kahramanmaras Sutcu imam Universitesi Tip Fakultesi Goz Klinigi/ Kahramanmaras/ Turkiye Adiyaman Universitesi Egitim ve Arastirma Hastanesi Goz Klinigi/ Adiyaman/ TurkiyePurpose: To evaluate the efficiency of the treatment of intravitreal ranibizumabin on the functions of lesion size and visual outcome in neovascular age-related macular degeneration cases. Material and Methods: Age-related macular degeneration diagnosis of 71eyes of 59 patients were analyzed retrospectively. Best-corrected visual acuity (BCVA), biomicroscopic examination, intra ocularpressure and fundus examinations were noted about the cases. In order to evaluate the effiency of IVR treatment, widest lesion diameter (WLD) of choroidal neovascularization (CNV) and BCVA were compared statistically, before and after treatment according to fundus fluorescein angiography (FFA). Results: The mean follow-upperiod was 14+/-5 months. Snellen BCVA was found 0.13+/-0.09 before treatment and was found 0.22+/-0.16 after treatment according to Snellen. A statistically significant increase was detected in BCVA after IVR teatment. WLD was calculated 4040+/-117 and #956;m before treatment and 3620+/-128 and #956;m after treatment. After IVR treatment a statistically significant decrease was founded in WLD. Conclusion: In our study, an increase in BCVA and a decrease in WLD were observed with the treatment of IVR in wet AMD cases. IVR was made out to be an effective and safe treatment. It can be thought that an obvious improvement was achieved acording to anatomic and visual acuity. [Cukurova Med J 2015; 40(4.000): 757-765]http://www.scopemed.org/fulltextpdf.php?mno=180917Age-related macular degenerationranibizumabvisual acuitychoroidal neovascularizationwidest lesion diameter |
| spellingShingle | Didem sahin Ahmet sahin Adnan Aksoy Lokman Aslan Ali simsek Efficiency of Intravitreal Ranibizumab Injection in Wet Age-Related Macular Degeneration Çukurova Üniversitesi Tıp Fakültesi Dergisi Age-related macular degeneration ranibizumab visual acuity choroidal neovascularization widest lesion diameter |
| title | Efficiency of Intravitreal Ranibizumab Injection in Wet Age-Related Macular Degeneration |
| title_full | Efficiency of Intravitreal Ranibizumab Injection in Wet Age-Related Macular Degeneration |
| title_fullStr | Efficiency of Intravitreal Ranibizumab Injection in Wet Age-Related Macular Degeneration |
| title_full_unstemmed | Efficiency of Intravitreal Ranibizumab Injection in Wet Age-Related Macular Degeneration |
| title_short | Efficiency of Intravitreal Ranibizumab Injection in Wet Age-Related Macular Degeneration |
| title_sort | efficiency of intravitreal ranibizumab injection in wet age related macular degeneration |
| topic | Age-related macular degeneration ranibizumab visual acuity choroidal neovascularization widest lesion diameter |
| url | http://www.scopemed.org/fulltextpdf.php?mno=180917 |
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