Decreased placental IL9 and IL9R in preeclampsia impair trophoblast cell proliferation, invasion, and angiogenesis

Decreased placental IL9 and IL9R in preeclampsia impair trophoblast cell proliferation, invasion, and angiogenesis

Objective Our study aimed to investigate IL9 and IL9R expression in preeclampsia and assess their effects on trophoblast biological behaviors. Methods IL9 and IL9R expression of placenta tissue were evaluated by immunochemistry and q-PCR. Using transwell, CCK-8, and tubule formation assays measured...

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Bibliographic Details
Main Authors: Yi Sun, Siyu Liu, Rong Hu, Qiongjie Zhou, Xiaotian Li
Format: Article
Language:English
Published: Taylor & Francis Group 2020-07-01
Series:Hypertension in Pregnancy
Subjects:
il9
il9 receptor
trophoblast
biological behaviors
Online Access:http://dx.doi.org/10.1080/10641955.2020.1754852

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